ENSGALG00000026445


Gallus gallus

Features
Gene ID: ENSGALG00000026445
  
Biological name :CALM1
  
Synonyms : CALM1 / Calmodulin / P62149
  
Possible biological names infered from orthology : CALM2 / calmodulin 2 / P0DP24
  
Species: Gallus gallus
  
Chr. number: 5
Strand: 1
Band:
Gene start: 43916855
Gene end: 43927634
  
Corresponding Affymetrix probe sets: Gga.12444.1.S2_s_at (Chicken Array)   Gga.12444.2.S1_a_at (Chicken Array)   Gga.5003.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000053652
Ensembl peptide - ENSGALP00000042446
NCBI entrez gene - 396523     See in Manteia.
RefSeq - NM_001110364
RefSeq Peptide - NP_001103834
swissprot - A0A1D5PLD6
swissprot - P62149
swissprot - R4GJW8
Ensembl - ENSGALG00000026445
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CALM2ENSG00000143933Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
CALM2 / P62149 / Calmodulin / Calm3* / CALM1* / P0DP23* / P0DP26* / P0DP27* / P0DP28* / calmodulin 1*ENSGALG00000010023100
CALML3 / calmodulin like 3 / P27482* / Q9D6P8* / Calmodulin-like protein 3 *ENSGALG0000000842488
TNNC2 / P02588 / Troponin C, skeletal muscle / P20801* / P02585* / troponin C2, fast skeletal type*ENSGALG0000000683552
TNNC1 / P09860 / Troponin C, slow skeletal and cardiac muscles / P63316* / P19123* / troponin C1, slow skeletal and cardiac type*ENSGALG0000000145952
CABP2 / calcium-binding protein 2 / Q9NPB3*ENSGALG0000003749745
CALML4 / calmodulin like 4 / Q91WQ9* / Q96GE6* / Calmodulin-like protein 4 *ENSGALG0000000797945
CABP1 / calcium binding protein 1 / Q9JLK7* / Q9NZU7*ENSGALG0000000711638


Protein motifs (from Interpro)
Interpro ID Name
 IPR002048  EF-hand domain
 IPR011992  EF-hand domain pair
 IPR018247  EF-Hand 1, calcium-binding site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 cellular_componentGO:0032991 protein-containing complex IDA
 molecular_functionGO:0005509 calcium ion binding IDA
 molecular_functionGO:0008022 protein C-terminus binding IPI
 molecular_functionGO:0017022 myosin binding IPI
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0051401 CH domain binding IPI
 molecular_functionGO:0097718 disordered domain specific binding IPI


Pathways (from Reactome)
Pathway description
CaMK IV-mediated phosphorylation of CREB
Calmodulin induced events
Cam-PDE 1 activation
Platelet degranulation
Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
PKA activation
Synthesis of IP3 and IP4 in the cytosol
eNOS activation
Inactivation, recovery and regulation of the phototransduction cascade
Stimuli-sensing channels
FCERI mediated Ca+2 mobilization
Ca2+ pathway
Reduction of cytosolic Ca++ levels
Sodium/Calcium exchangers
CREB phosphorylation through the activation of CaMKK
CREB phosphorylation through the activation of CaMKII
Activation of CaMK IV
Ras activation upon Ca2+ influx through NMDA receptor
Smooth Muscle Contraction
Activation of Ca-permeable Kainate Receptor
VEGFR2 mediated vascular permeability
Phase 0 - rapid depolarisation
Ion homeostasis
CLEC7A (Dectin-1) induces NFAT activation
RHO GTPases activate IQGAPs
RHO GTPases activate PAKs
RAF/MAP kinase cascade
Glycogen breakdown (glycogenolysis)
Protein methylation
Ion transport by P-type ATPases


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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