ENSGALG00000026928


Gallus gallus

Features
Gene ID: ENSGALG00000026928
  
Biological name :KLF4
  
Synonyms : KLF4 / Kruppel like factor 4
  
Possible biological names infered from orthology : Krueppel-like factor 4 / O43474 / Q60793
  
Species: Gallus gallus
  
Chr. number: Z
Strand: -1
Band:
Gene start: 55703411
Gene end: 55706995
  
Corresponding Affymetrix probe sets: Gga.17274.1.S1_at (Chicken Array)   GgaAffx.9898.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000041546
NCBI entrez gene - 770254     See in Manteia.
RefSeq - XM_001233583
RefSeq - XM_004949369
swissprot - R4GHJ8
Ensembl - ENSGALG00000026928
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 klf4ENSDARG00000079922Danio rerio
 KLF4ENSG00000136826Homo sapiens
 Klf4ENSMUSG00000003032Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
KLF2 / Krueppel-like factor 2 ENSGALG0000000393941
KLF5* / Q13887* / Q9Z0Z7* / Kruppel like factor 5* / Krueppel-like factor 5 *ENSGALG0000001692726
KLF1* / Q13351* / Kruppel like factor 1*ENSGALG0000001010126
KLF3 / Kruppel like factor 3 / P57682* / Q60980* / Krueppel-like factor 3 *ENSGALG0000004171725
KLF12 / Kruppel like factor 12 / O35738* / Q9Y4X4* / Krueppel-like factor 12 *ENSGALG0000001692624
ENSGALG0000000757023
KLF6 / Kruppel like factor 6 / Q99612*ENSGALG0000003317822
KLF7 / Gallus gallus Kruppel like factor 7 (KLF7), mRNA. / Q99JB0* / O75840* / Kruppel like factor 7* / Krueppel-like factor 7 *ENSGALG0000000850122
ENSGALG0000004645519
KLF15 / Kruppel like factor 15 / Q9EPW2* / Q9UIH9* / Krueppel-like factor 15 *ENSGALG0000003613319
KLF8* / O95600* / Q8BLM0* / Kruppel like factor 8* / Krueppel-like factor 8 *ENSGALG0000004407813


Protein motifs (from Interpro)
Interpro ID Name
 IPR013087  Zinc finger C2H2-type


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IEA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006357 regulation of transcription by RNA polymerase II IEA
 biological_processGO:0006366 transcription by RNA polymerase II IEA
 biological_processGO:0008285 negative regulation of cell proliferation IEA
 biological_processGO:0009913 epidermal cell differentiation IEA
 biological_processGO:0010033 response to organic substance IEA
 biological_processGO:0010628 positive regulation of gene expression IEA
 biological_processGO:0010629 negative regulation of gene expression IEA
 biological_processGO:0016525 negative regulation of angiogenesis IEA
 biological_processGO:0019827 stem cell population maintenance IEA
 biological_processGO:0030154 cell differentiation IEA
 biological_processGO:0030336 negative regulation of cell migration IEA
 biological_processGO:0031077 post-embryonic camera-type eye development IEA
 biological_processGO:0032088 negative regulation of NF-kappaB transcription factor activity IEA
 biological_processGO:0032270 positive regulation of cellular protein metabolic process IEA
 biological_processGO:0032526 response to retinoic acid IEA
 biological_processGO:0034115 negative regulation of heterotypic cell-cell adhesion IEA
 biological_processGO:0035166 post-embryonic hemopoiesis IEA
 biological_processGO:0042127 regulation of cell proliferation IEA
 biological_processGO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process IEA
 biological_processGO:0043433 negative regulation of DNA-binding transcription factor activity IEA
 biological_processGO:0045415 negative regulation of interleukin-8 biosynthetic process IEA
 biological_processGO:0045429 positive regulation of nitric oxide biosynthetic process IEA
 biological_processGO:0045444 fat cell differentiation IEA
 biological_processGO:0045595 regulation of cell differentiation IEA
 biological_processGO:0045892 negative regulation of transcription, DNA-templated IEA
 biological_processGO:0045893 positive regulation of transcription, DNA-templated IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IEA
 biological_processGO:0046985 positive regulation of hemoglobin biosynthetic process IEA
 biological_processGO:0048679 regulation of axon regeneration IEA
 biological_processGO:0048730 epidermis morphogenesis IEA
 biological_processGO:0051247 positive regulation of protein metabolic process IEA
 biological_processGO:0051973 positive regulation of telomerase activity IEA
 biological_processGO:0060070 canonical Wnt signaling pathway IEA
 biological_processGO:0060761 negative regulation of response to cytokine stimulus IEA
 biological_processGO:0061614 pri-miRNA transcription by RNA polymerase II IEA
 biological_processGO:0071363 cellular response to growth factor stimulus IEA
 biological_processGO:0071499 cellular response to laminar fluid shear stress IEA
 biological_processGO:0090051 negative regulation of cell migration involved in sprouting angiogenesis IEA
 biological_processGO:1903672 positive regulation of sprouting angiogenesis IEA
 biological_processGO:1904798 positive regulation of core promoter binding IEA
 biological_processGO:1904998 negative regulation of leukocyte adhesion to arterial endothelial cell IEA
 biological_processGO:1990830 cellular response to leukemia inhibitory factor IEA
 biological_processGO:2000134 negative regulation of G1/S transition of mitotic cell cycle IEA
 biological_processGO:2000342 negative regulation of chemokine (C-X-C motif) ligand 2 production IEA
 cellular_componentGO:0000790 nuclear chromatin IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005719 nuclear euchromatin IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0044798 nuclear transcription factor complex IEA
 molecular_functionGO:0000978 RNA polymerase II proximal promoter sequence-specific DNA binding IEA
 molecular_functionGO:0000987 proximal promoter sequence-specific DNA binding IEA
 molecular_functionGO:0001010 transcription factor activity, sequence-specific DNA-binding transcription factor recruiting IEA
 molecular_functionGO:0001077 transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding IEA
 molecular_functionGO:0001085 RNA polymerase II transcription factor binding IEA
 molecular_functionGO:0001190 transcriptional activator activity, RNA polymerase II transcription factor binding IEA
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IEA
 molecular_functionGO:0008013 beta-catenin binding IEA
 molecular_functionGO:0008134 transcription factor binding IEA
 molecular_functionGO:0043565 sequence-specific DNA binding IEA
 molecular_functionGO:0044212 transcription regulatory region DNA binding IEA
 molecular_functionGO:1990841 promoter-specific chromatin binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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