ENSGALG00000028037


Gallus gallus

Features
Gene ID: ENSGALG00000028037
  
Biological name :FOS
  
Synonyms : FOS / P11939 / Proto-oncogene c-Fos
  
Possible biological names infered from orthology : Fos proto-oncogene, AP-1 transcription factor subunit / P01100 / P01101 / Proto-onco c-Fos
  
Species: Gallus gallus
  
Chr. number: 5
Strand: 1
Band:
Gene start: 38264804
Gene end: 38267713
  
Corresponding Affymetrix probe sets: Gga.748.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000041340
NCBI entrez gene - 396512     See in Manteia.
RefSeq - NM_205508
RefSeq Peptide - NP_990839
swissprot - P11939
swissprot - R4GH11
Ensembl - ENSGALG00000028037
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 fosabENSDARG00000031683Danio rerio
 FOSENSG00000170345Homo sapiens
 FosENSMUSG00000021250Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
FOSL2 / P18625 / Fos-related antigen 2 / P15408* / P47930* / FOS like 2, AP-1 transcription factor subunit*ENSGALG0000001003640


Protein motifs (from Interpro)
Interpro ID Name
 IPR000837  AP-1 transcription factor
 IPR004827  Basic-leucine zipper domain
 IPR029816  c-Fos/v-Fos


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006357 regulation of transcription by RNA polymerase II IEA
 biological_processGO:0006366 transcription by RNA polymerase II IEA
 biological_processGO:0007179 transforming growth factor beta receptor signaling pathway IEA
 biological_processGO:0007399 nervous system development IEA
 biological_processGO:0031668 cellular response to extracellular stimulus IEA
 biological_processGO:0034614 cellular response to reactive oxygen species IEA
 biological_processGO:0035914 skeletal muscle cell differentiation IEA
 biological_processGO:0035994 response to muscle stretch IEA
 biological_processGO:0042493 response to drug IEA
 biological_processGO:0045672 positive regulation of osteoclast differentiation IEA
 biological_processGO:0045893 positive regulation of transcription, DNA-templated IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IEA
 biological_processGO:0060395 SMAD protein signal transduction IEA
 biological_processGO:0071276 cellular response to cadmium ion IEA
 biological_processGO:0071277 cellular response to calcium ion IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005667 transcription factor complex IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0032993 protein-DNA complex IEA
 cellular_componentGO:0035976 transcription factor AP-1 complex IEA
 molecular_functionGO:0000978 RNA polymerase II proximal promoter sequence-specific DNA binding IEA
 molecular_functionGO:0000979 RNA polymerase II core promoter sequence-specific DNA binding IEA
 molecular_functionGO:0001077 transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding IEA
 molecular_functionGO:0001102 RNA polymerase II activating transcription factor binding IEA
 molecular_functionGO:0001190 transcriptional activator activity, RNA polymerase II transcription factor binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003682 chromatin binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IEA
 molecular_functionGO:0008134 transcription factor binding IEA
 molecular_functionGO:0044212 transcription regulatory region DNA binding IEA
 molecular_functionGO:0046982 protein heterodimerization activity IEA
 molecular_functionGO:0070412 R-SMAD binding IEA


Pathways (from Reactome)
Pathway description
Oxidative Stress Induced Senescence
FCERI mediated MAPK activation
Activation of the AP-1 family of transcription factors
Estrogen-dependent gene expression


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000001501 MAPK1 / mitogen-activated protein kinase 1 / P28482* / P63085* / Mus musculus mitogen-activated protein kinase 1 (Mapk1), transcript variant 3, mRNA.*  / reaction






 

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