ENSDARG00000031683


Danio rerio

Features
Gene ID: ENSDARG00000031683
  
Biological name :fosab
  
Synonyms : fosab / v-fos FBJ murine osteosarcoma viral oncogene homolog Ab
  
Possible biological names infered from orthology : FOS / Fos proto-oncogene, AP-1 transcription factor subunit / P01100 / P01101 / Proto-onco c-Fos
  
Species: Danio rerio
  
Chr. number: 20
Strand: -1
Band:
Gene start: 46552311
Gene end: 46554440
  
Corresponding Affymetrix probe sets: Dr.12986.1.A1_at (Zebrafish Array)   Dr.12986.1.A1_a_at (Zebrafish Array)   Dr.12986.2.S1_at (Zebrafish Array)   Dr.12986.3.S1_a_at (Zebrafish Array)   NM_205569_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000043297
Ensembl peptide - ENSDARP00000060679
NCBI entrez gene - 394198     See in Manteia.
RefSeq - NM_205569
RefSeq Peptide - NP_991132
swissprot - Q5SP68
swissprot - Q6P0S4
ZFIN ID - ZDB-GENE-031222-4
Ensembl - ENSDARG00000031683
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 FOSENSGALG00000028037Gallus gallus
 FOSENSG00000170345Homo sapiens
 FosENSMUSG00000021250Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
fosaa / v-fos FBJ murine osteosarcoma viral oncogene homolog AaENSDARG0000004013540
fosb / FBJ murine osteosarcoma viral oncogene homolog B / P13346* / P53539* / Protein fosB * / FosB proto-oncogene, AP-1 transcription factor subunit*ENSDARG0000005575139
fosl2 / fos-like antigen 2 / P15408* / FOS like 2, AP-1 transcription factor subunit*ENSDARG0000004062336
fosl1a / FOS-like antigen 1a / FOSL1* / P15407* / P48755* / Fos-related antigen 1 * / FOS like 1, AP-1 transcription factor subunit*ENSDARG0000001535533
si:ch211-153j24.3ENSDARG0000006842831
fosl1b / FOS-like antigen 1bENSDARG0000007937319
si:ch211-59d15.4ENSDARG0000009217417


Protein motifs (from Interpro)
Interpro ID Name
 IPR000837  AP-1 transcription factor
 IPR004827  Basic-leucine zipper domain
 IPR029816  c-Fos/v-Fos


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006357 regulation of transcription by RNA polymerase II IEA
 biological_processGO:0033555 multicellular organismal response to stress IEP
 cellular_componentGO:0005667 transcription factor complex IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003690 double-stranded DNA binding IDA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IEA


Pathways (from Reactome)
Pathway description
Oxidative Stress Induced Senescence
FCERI mediated MAPK activation
Activation of the AP-1 family of transcription factors


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0005147 regenerating tissue regenerating tissue cardiac muscle cell proliferation decreased occurrence , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000027552 mapk1 / mitogen-activated protein kinase 1 / P28482* / P63085* / Mus musculus mitogen-activated protein kinase 1 (Mapk1), transcript variant 3, mRNA.*  / reaction
 ENSDARG00000043531 jun / Jun proto-oncogene, AP-1 transcription factor subunit / P05412* / P05627* / jun proto-oncogene*  / complex / reaction
 ENSDARG00000070573 mapk3 / mitogen-activated protein kinase 3 / P27361* / Q63844*  / reaction






 

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