ENSGALG00000029435


Gallus gallus

Features
Gene ID: ENSGALG00000029435
  
Biological name :CYP7B1
  
Synonyms : CYP7B1 / cytochrome P450 family 7 subfamily B member 1
  
Possible biological names infered from orthology : 25-hydroxycholesterol 7-alpha-hydroxylase / O75881 / Q60991
  
Species: Gallus gallus
  
Chr. number: 2
Strand: -1
Band:
Gene start: 114794326
Gene end: 114922700
  
Corresponding Affymetrix probe sets: GgaAffx.9874.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000045505
NCBI entrez gene - 420164     See in Manteia.
RefSeq - XM_015282719
swissprot - A0A1D5NYP5
Ensembl - ENSGALG00000029435
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 cyp7b1ENSDARG00000008858Danio rerio
 CYP7B1ENSG00000172817Homo sapiens
 Cyp7b1ENSMUSG00000039519Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
CYP7A1 / cholesterol 7-alpha-monooxygenase / P22680* / Q64505* / cytochrome P450 family 7 subfamily A member 1*ENSGALG0000004122242
CYP8B1 / cytochrome P450, family 8, subfamily B / Q9UNU6* / cytochrome P450 family 8 subfamily B member 1*ENSGALG0000003351126
CYP39A1 / cytochrome P450 family 39 subfamily A member 1 / Q9JKJ9* / Q9NYL5* / 24-hydroxycholesterol 7-alpha-hydroxylase *ENSGALG0000001671020


Protein motifs (from Interpro)
Interpro ID Name
 IPR001128  Cytochrome P450
 IPR002403  Cytochrome P450, E-class, group IV
 IPR024204  Cytochrome P450, cholesterol 7-alpha-monooxygenase-type


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006699 bile acid biosynthetic process IEA
 biological_processGO:0033147 negative regulation of intracellular estrogen receptor signaling pathway IEA
 biological_processGO:0035754 B cell chemotaxis IEA
 biological_processGO:0050679 positive regulation of epithelial cell proliferation IEA
 biological_processGO:0055114 oxidation-reduction process IEA
 biological_processGO:0060740 prostate gland epithelium morphogenesis IEA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005789 endoplasmic reticulum membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0004497 monooxygenase activity IEA
 molecular_functionGO:0005506 iron ion binding IEA
 molecular_functionGO:0008396 oxysterol 7-alpha-hydroxylase activity IEA
 molecular_functionGO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen IEA
 molecular_functionGO:0020037 heme binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Synthesis of bile acids and bile salts
Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
Synthesis of bile acids and bile salts via 27-hydroxycholesterol
Endogenous sterols


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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