ENSDARG00000008858


Danio rerio

Features
Gene ID: ENSDARG00000008858
  
Biological name :cyp7b1
  
Synonyms : cyp7b1 / cytochrome P450, family 7, subfamily B, polypeptide 1
  
Possible biological names infered from orthology : 25-hydroxycholesterol 7-alpha-hydroxylase / cytochrome P450 family 7 subfamily B member 1 / O75881 / Q60991
  
Species: Danio rerio
  
Chr. number: 2
Strand: 1
Band:
Gene start: 42135719
Gene end: 42152135
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000020000
NCBI entrez gene - 570455     See in Manteia.
swissprot - E7FEI0
ZFIN ID - ZDB-GENE-070912-293
Ensembl - ENSDARG00000008858
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CYP7B1ENSGALG00000029435Gallus gallus
 CYP7B1ENSG00000172817Homo sapiens
 Cyp7b1ENSMUSG00000039519Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
CR354540.1ENSDARG0000000405138
cyp7a1 / cytochrome P450, family 7, subfamily A, polypeptide 1 / P22680* / Q64505* / Cholesterol 7-alpha-monooxygenase * / cytochrome P450 family 7 subfamily A member 1*ENSDARG0000006901838
cyp8b3 / cytochrome P450, family 8, subfamily B, polypeptide 3 / CYP8B1* / Q9UNU6* / cytochrome P450 family 8 subfamily B member 1*ENSDARG0000009755933
cyp8b1 / cytochrome P450, family 8, subfamily B, polypeptide 1 / Q9UNU6* / cytochrome P450 family 8 subfamily B member 1*ENSDARG0000005306833
cyp8b2 / cytochrome P450, family 8, subfamily B, polypeptide 2 / CYP8B1* / Q9UNU6* / cytochrome P450 family 8 subfamily B member 1*ENSDARG0000009755633
ptgis / F1RE08 / prostaglandin I2 (prostacyclin) synthase / O35074* / Q16647* / prostaglandin I2 synthase*ENSDARG0000006009430
cyp39a1 / cytochrome P450, family 39, subfamily A, polypeptide 1 / Q9NYL5* / cytochrome P450 family 39 subfamily A member 1*ENSDARG0000001798222


Protein motifs (from Interpro)
Interpro ID Name
 IPR001128  Cytochrome P450
 IPR002403  Cytochrome P450, E-class, group IV
 IPR017972  Cytochrome P450, conserved site
 IPR024204  Cytochrome P450, cholesterol 7-alpha-monooxygenase-type


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0055114 oxidation-reduction process IEA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005789 endoplasmic reticulum membrane IEA
 cellular_componentGO:0016020 membrane IEA
 molecular_functionGO:0004497 monooxygenase activity IEA
 molecular_functionGO:0005506 iron ion binding IEA
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen IEA
 molecular_functionGO:0020037 heme binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Synthesis of bile acids and bile salts
Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
Synthesis of bile acids and bile salts via 27-hydroxycholesterol
Endogenous sterols


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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