ENSGALG00000030407


Gallus gallus

Features
Gene ID: ENSGALG00000030407
  
Biological name :IL6R
  
Synonyms : IL6R / interleukin-6 receptor subunit alpha precursor
  
Possible biological names infered from orthology : Il6ra / interleukin 6 receptor / Interleukin-6 receptor subunit alpha / P08887 / P22272
  
Species: Gallus gallus
  
Chr. number: 25
Strand: 1
Band:
Gene start: 1708520
Gene end: 1714083
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSGALP00000053938
Ensembl peptide - ENSGALP00000057608
NCBI entrez gene - 693252     See in Manteia.
RefSeq - NM_001044675
RefSeq - XM_015298493
RefSeq Peptide - NP_001038140
swissprot - A0A1D5PXB4
swissprot - A0A1D5PM65
Ensembl - ENSGALG00000030407
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 il6rENSDARG00000104474Danio rerio
 IL6RENSG00000160712Homo sapiens
 Il6raENSMUSG00000027947Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
IL11RA / interleukin 11 receptor subunit alpha / Q64385* / P70225* / Q14626* / Gm13305* / Il11ra2* / Il11ra1* / predicted gene 13305* / Interleukin-11 receptor subunit alpha-1 * / Interleuk...ENSGALG0000000584821
CNTFR / ciliary neurotrophic factor receptor subunit alpha precursor / O88507* / P26992* / ciliary neurotrophic factor receptor* / Ciliary neurotrophic factor receptor subunit alpha *ENSGALG0000002814018


Protein motifs (from Interpro)
Interpro ID Name
 IPR003530  Long hematopoietin receptor, soluble alpha chain, conserved site
 IPR003599  Immunoglobulin subtype
 IPR003961  Fibronectin type III
 IPR007110  Immunoglobulin-like domain
 IPR013783  Immunoglobulin-like fold
 IPR015321  Type I cytokine receptor, cytokine-binding domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0008284 positive regulation of cell proliferation IEA
 biological_processGO:0019221 cytokine-mediated signaling pathway IEA
 biological_processGO:0031018 endocrine pancreas development IEA
 biological_processGO:0032722 positive regulation of chemokine production IEA
 biological_processGO:0032755 positive regulation of interleukin-6 production IEA
 biological_processGO:0034097 response to cytokine IEA
 biological_processGO:0042531 positive regulation of tyrosine phosphorylation of STAT protein IEA
 biological_processGO:0048661 positive regulation of smooth muscle cell proliferation IEA
 biological_processGO:0050731 positive regulation of peptidyl-tyrosine phosphorylation IEA
 biological_processGO:0070102 interleukin-6-mediated signaling pathway IEA
 biological_processGO:0070120 ciliary neurotrophic factor-mediated signaling pathway IEA
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005896 interleukin-6 receptor complex IEA
 cellular_componentGO:0009986 cell surface IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0016324 apical plasma membrane IEA
 cellular_componentGO:0070110 ciliary neurotrophic factor receptor complex IEA
 molecular_functionGO:0004896 cytokine receptor activity IEA
 molecular_functionGO:0004897 ciliary neurotrophic factor receptor activity IEA
 molecular_functionGO:0004915 interleukin-6 receptor activity IEA
 molecular_functionGO:0005138 interleukin-6 receptor binding IEA
 molecular_functionGO:0019899 enzyme binding IEA
 molecular_functionGO:0019981 interleukin-6 binding IEA
 molecular_functionGO:0042803 protein homodimerization activity IEA
 molecular_functionGO:0070119 ciliary neurotrophic factor binding IEA


Pathways (from Reactome)
Pathway description
Interleukin-6 signaling
MAPK1 (ERK2) activation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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