ENSDARG00000104474


Danio rerio

Features
Gene ID: ENSDARG00000104474
  
Biological name :il6r
  
Synonyms : il6r / interleukin 6 receptor
  
Possible biological names infered from orthology : Il6ra / Interleukin-6 receptor subunit alpha / P08887 / P22272
  
Species: Danio rerio
  
Chr. number: 16
Strand: -1
Band:
Gene start: 22177254
Gene end: 22194400
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000154692
Ensembl peptide - ENSDARP00000138400
NCBI entrez gene - 100135755     See in Manteia.
RefSeq - NM_001330258
RefSeq Peptide - NP_001317187
swissprot - A0A0R4IQ60
ZFIN ID - ZDB-GENE-080107-7
Ensembl - ENSDARG00000104474
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 IL6RENSGALG00000030407Gallus gallus
 IL6RENSG00000160712Homo sapiens
 Il6raENSMUSG00000027947Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
il11ra / interleukin 11 receptor, alpha / P70225* / Q64385* / Q14626* / Gm13305* / Il11ra1* / Il11ra2* / AL162231.3* / predicted gene 13305* / interleukin 11 receptor subunit alpha* / Inter...ENSDARG0000002673613
cntfr / ciliary neurotrophic factor receptor / O88507* / P26992* / Ciliary neurotrophic factor receptor subunit alpha *ENSDARG0000002866112
ebi3 / Epstein-Barr virus induced 3 / O35228* / Q14213* / Interleukin-27 subunit beta *ENSDARG000000536209


Protein motifs (from Interpro)
Interpro ID Name
 IPR003530  Long hematopoietin receptor, soluble alpha chain, conserved site
 IPR003961  Fibronectin type III
 IPR007110  Immunoglobulin-like domain
 IPR013783  Immunoglobulin-like fold


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0019221 cytokine-mediated signaling pathway IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0004896 cytokine receptor activity IEA


Pathways (from Reactome)
Pathway description
Interleukin-6 signaling
MAPK3 (ERK1) activation
MAPK1 (ERK2) activation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000076182 stat1b / signal transducer and activator of transcription 1b / STAT1* / P42224* / signal transducer and activator of transcription 1*  / complex / reaction
 ENSDARG00000018882 jak2b / Janus kinase 2b / JAK2* / O60674* / Janus kinase 2*  / complex / reaction
 ENSDARG00000025428 socs3a / suppressor of cytokine signaling 3a / SOCS3* / O14543* / suppressor of cytokine signaling 3*  / reaction / complex
 ENSDARG00000020625 jak1 / Janus kinase 1 / P23458*  / complex / reaction
 ENSDARG00000026611 socs3b / suppressor of cytokine signaling 3b / SOCS3* / O35718* / O14543* / suppressor of cytokine signaling 3*  / reaction / complex
 ENSDARG00000020334 ptpn11a / protein tyrosine phosphatase, non-receptor type 11, a / PTPN11* / P35235* / Q06124* / Tyrosine-protein phosphatase non-receptor type 11 * / protein tyrosine phosphatase, non-recep...  / reaction / complex
 ENSDARG00000104693 il6st / interleukin 6 signal transducer / P40189* / Q00560* / Interleukin-6 receptor subunit beta *  / reaction / complex
 ENSDARG00000104808 jak2a / Janus kinase 2a / JAK2* / O60674* / Janus kinase 2*  / complex / reaction
 ENSDARG00000104474 il6r / interleukin 6 receptor / P08887*  / complex / reaction






 

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