ENSDARG00000028661


Danio rerio

Features
Gene ID: ENSDARG00000028661
  
Biological name :cntfr
  
Synonyms : ciliary neurotrophic factor receptor / cntfr
  
Possible biological names infered from orthology : Ciliary neurotrophic factor receptor subunit alpha / O88507 / P26992
  
Species: Danio rerio
  
Chr. number: 10
Strand: -1
Band:
Gene start: 13460130
Gene end: 13772861
  
Corresponding Affymetrix probe sets: Dr.20443.1.A1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000148232
Ensembl peptide - ENSDARP00000114970
NCBI entrez gene - 368438     See in Manteia.
RefSeq - NM_001098242
RefSeq Peptide - NP_001091712
swissprot - A4JYQ0
ZFIN ID - ZDB-GENE-030616-82
Ensembl - ENSDARG00000028661
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CNTFRENSGALG00000028140Gallus gallus
 CNTFRENSG00000122756Homo sapiens
 CntfrENSMUSG00000028444Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
il11ra / interleukin 11 receptor, alpha / P70225* / Q64385* / Q14626* / Gm13305* / Il11ra1* / Il11ra2* / AL162231.3* / predicted gene 13305* / interleukin 11 receptor subunit alpha* / Inter...ENSDARG0000002673627
ebi3 / Epstein-Barr virus induced 3 / O35228* / Q14213* / Interleukin-27 subunit beta *ENSDARG0000005362022
il6r / interleukin 6 receptor / P08887*ENSDARG0000010447420


Protein motifs (from Interpro)
Interpro ID Name
 IPR003530  Long hematopoietin receptor, soluble alpha chain, conserved site
 IPR003961  Fibronectin type III
 IPR007110  Immunoglobulin-like domain
 IPR013783  Immunoglobulin-like fold


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0019221 cytokine-mediated signaling pathway IEA
 biological_processGO:0048680 positive regulation of axon regeneration IMP
 cellular_componentGO:0016020 membrane IEA
 molecular_functionGO:0004896 cytokine receptor activity IEA


Pathways (from Reactome)
Pathway description
IL-6-type cytokine receptor ligand interactions


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000006368 crlf1b / cytokine receptor-like factor 1b / CRLF1* / O75462* / Q9JM58* / cytokine receptor like factor 1*  / complex / reaction
 ENSDARG00000024365 crlf1a / cytokine receptor-like factor 1a / CRLF1* / O75462* / Q9JM58* / cytokine receptor like factor 1*  / complex / reaction
 ENSDARG00000104808 jak2a / Janus kinase 2a / JAK2* / O60674* / Janus kinase 2*  / reaction / complex
 ENSDARG00000020625 jak1 / Janus kinase 1 / P23458*  / complex / reaction
 ENSDARG00000018882 jak2b / Janus kinase 2b / JAK2* / O60674* / Janus kinase 2*  / complex / reaction
 ENSDARG00000104693 il6st / interleukin 6 signal transducer / P40189* / Q00560* / Interleukin-6 receptor subunit beta *  / reaction / complex
 ENSDARG00000076140 clcf1 / cardiotrophin-like cytokine factor 1 / Ctf2* / Q9UBD9* / P83714* / Q9QZM3* / Cardiotrophin-2 *  / complex / reaction






 

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