ENSGALG00000031918


Gallus gallus

Features
Gene ID: ENSGALG00000031918
  
Biological name :RAD51D
  
Synonyms : RAD51D / RAD51 paralog D
  
Possible biological names infered from orthology : O55230 / O75771
  
Species: Gallus gallus
  
Chr. number: 19
Strand: 1
Band:
Gene start: 4447460
Gene end: 4451549
  
Corresponding Affymetrix probe sets: Gga.9680.1.S1_a_at (Chicken Array)   Gga.9680.1.S1_x_at (Chicken Array)   Gga.9680.3.S1_a_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000049100
NCBI entrez gene - 417528     See in Manteia.
RefSeq - NM_001198646
RefSeq - XM_015295720
RefSeq - XM_015295721
RefSeq Peptide - NP_001185575
swissprot - A0A1D5P8Q1
Ensembl - ENSGALG00000031918
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 rad51dENSDARG00000026400Danio rerio
 O75771ENSG00000185379Homo sapiens
 O55230ENSMUSG00000018841Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
RAD51C / RAD51 paralog C / O43502* / Q924H5* / DNA repair 3 *ENSGALG0000004038023
RAD51B / RAD51 paralog B / O15315* / O35719* / DNA repair 2 *ENSGALG0000000949121
XRCC3 / X-ray repair cross complementing 3 / O43542* / Q9CXE6* / X-ray repair complementing defective repair in Chinese hamster cells 3*ENSGALG0000001153318


Protein motifs (from Interpro)
Interpro ID Name
 IPR003593  AAA+ ATPase domain
 IPR013632  DNA recombination and repair protein Rad51-like, C-terminal
 IPR020588  DNA recombination and repair protein RecA-like, ATP-binding domain
 IPR027417  P-loop containing nucleoside triphosphate hydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000723 telomere maintenance IEA
 biological_processGO:0000724 double-strand break repair via homologous recombination IEA
 biological_processGO:0006281 DNA repair IEA
 biological_processGO:0006289 nucleotide-excision repair IEA
 biological_processGO:0006974 cellular response to DNA damage stimulus IEA
 biological_processGO:0036297 interstrand cross-link repair IEA
 biological_processGO:0042148 strand invasion IEA
 biological_processGO:0051276 chromosome organization IEA
 biological_processGO:0051726 regulation of cell cycle IEA
 cellular_componentGO:0000781 chromosome, telomeric region IEA
 cellular_componentGO:0000784 nuclear chromosome, telomeric region IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005657 replication fork IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005813 centrosome IEA
 cellular_componentGO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex IEA
 molecular_functionGO:0000400 four-way junction DNA binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003697 single-stranded DNA binding IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0008094 DNA-dependent ATPase activity IEA
 molecular_functionGO:0043015 gamma-tubulin binding IEA


Pathways (from Reactome)
Pathway description
HDR through Homologous Recombination (HRR)
Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)
Resolution of D-loop Structures through Holliday Junction Intermediates
Homologous DNA Pairing and Strand Exchange
Presynaptic phase of homologous DNA pairing and strand exchange


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000026865 XRCC2 / X-ray repair cross complementing 2 / O43543* / Q9CX47* / X-ray repair complementing defective repair in Chinese hamster cells 2*  / complex / reaction
 ENSGALG00000040380 RAD51C / RAD51 paralog C / O43502* / Q924H5* / DNA repair 3 *  / complex / reaction
 ENSGALG00000017290 RAD51AP1 / RAD51 associated protein 1 / Q96B01* / RAD51-associated protein 1 isoform 2 *  / reaction






 

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