ENSGALG00000026865


Gallus gallus

Features
Gene ID: ENSGALG00000026865
  
Biological name :XRCC2
  
Synonyms : X-ray repair cross complementing 2 / XRCC2
  
Possible biological names infered from orthology : O43543 / Q9CX47 / X-ray repair complementing defective repair in Chinese hamster cells 2
  
Species: Gallus gallus
  
Chr. number: 2
Strand: -1
Band:
Gene start: 6803388
Gene end: 6813943
  
Corresponding Affymetrix probe sets: Gga.12290.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000041071
Ensembl peptide - ENSGALP00000064530
NCBI entrez gene - 420438     See in Manteia.
RefSeq - XM_418543
swissprot - A0A1L1S068
swissprot - R4GGA5
Ensembl - ENSGALG00000026865
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 XRCC2ENSDARG00000013933Danio rerio
 XRCC2ENSG00000196584Homo sapiens
 Xrcc2ENSMUSG00000028933Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR013632  DNA recombination and repair protein Rad51-like, C-terminal
 IPR020588  DNA recombination and repair protein RecA-like, ATP-binding domain
 IPR027417  P-loop containing nucleoside triphosphate hydrolase
 IPR030547  DNA repair protein XRCC2


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000278 mitotic cell cycle IEA
 biological_processGO:0000707 meiotic DNA recombinase assembly IBA
 biological_processGO:0000724 double-strand break repair via homologous recombination IEA
 biological_processGO:0001701 in utero embryonic development IEA
 biological_processGO:0001756 somitogenesis IEA
 biological_processGO:0006281 DNA repair IEA
 biological_processGO:0006312 mitotic recombination IBA
 biological_processGO:0006974 cellular response to DNA damage stimulus IEA
 biological_processGO:0007098 centrosome cycle IEA
 biological_processGO:0007131 reciprocal meiotic recombination IBA
 biological_processGO:0010165 response to X-ray IEA
 biological_processGO:0010212 response to ionizing radiation IBA
 biological_processGO:0010332 response to gamma radiation IEA
 biological_processGO:0022008 neurogenesis IEA
 biological_processGO:0035264 multicellular organism growth IEA
 biological_processGO:0042148 strand invasion IEA
 biological_processGO:0043524 negative regulation of neuron apoptotic process IEA
 biological_processGO:0050769 positive regulation of neurogenesis IEA
 biological_processGO:2000269 regulation of fibroblast apoptotic process IEA
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005657 replication fork IEA
 cellular_componentGO:0005813 centrosome IEA
 cellular_componentGO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex IEA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IEA
 molecular_functionGO:0000150 recombinase activity IBA
 molecular_functionGO:0000400 four-way junction DNA binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003690 double-stranded DNA binding IBA
 molecular_functionGO:0003697 single-stranded DNA binding IBA
 molecular_functionGO:0004520 endodeoxyribonuclease activity IBA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0008094 DNA-dependent ATPase activity IEA


Pathways (from Reactome)
Pathway description
HDR through Homologous Recombination (HRR)
Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)
Resolution of D-loop Structures through Holliday Junction Intermediates
Homologous DNA Pairing and Strand Exchange
Presynaptic phase of homologous DNA pairing and strand exchange


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000040380 RAD51C / RAD51 paralog C / O43502* / Q924H5* / DNA repair 3 *  / complex / reaction
 ENSGALG00000017290 RAD51AP1 / RAD51 associated protein 1 / Q96B01* / RAD51-associated protein 1 isoform 2 *  / reaction
 ENSGALG00000031918 RAD51D / RAD51 paralog D / O55230* / O75771*  / complex / reaction






 

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