ENSDARG00000013933


Danio rerio

Features
Gene ID: ENSDARG00000013933
  
Biological name :XRCC2
  
Synonyms : X-ray repair cross complementing 2 / XRCC2
  
Possible biological names infered from orthology : O43543 / Q9CX47 / X-ray repair complementing defective repair in Chinese hamster cells 2
  
Species: Danio rerio
  
Chr. number: 24
Strand: 1
Band:
Gene start: 7322116
Gene end: 7330156
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000019152
Ensembl peptide - ENSDARP00000155837
NCBI entrez gene - 553395     See in Manteia.
swissprot - F1Q9N3
Ensembl - ENSDARG00000013933
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 XRCC2ENSGALG00000026865Gallus gallus
 XRCC2ENSG00000196584Homo sapiens
 Xrcc2ENSMUSG00000028933Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR013632  DNA recombination and repair protein Rad51-like, C-terminal
 IPR020588  DNA recombination and repair protein RecA-like, ATP-binding domain
 IPR027417  P-loop containing nucleoside triphosphate hydrolase
 IPR030547  DNA repair protein XRCC2


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000707 meiotic DNA recombinase assembly IBA
 biological_processGO:0000724 double-strand break repair via homologous recombination IEA
 biological_processGO:0006281 DNA repair IEA
 biological_processGO:0006312 mitotic recombination IBA
 biological_processGO:0007131 reciprocal meiotic recombination IBA
 biological_processGO:0010212 response to ionizing radiation IBA
 biological_processGO:0042148 strand invasion IBA
 cellular_componentGO:0005657 replication fork IBA
 cellular_componentGO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex IBA
 molecular_functionGO:0000150 recombinase activity IBA
 molecular_functionGO:0000400 four-way junction DNA binding IBA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003690 double-stranded DNA binding IBA
 molecular_functionGO:0003697 single-stranded DNA binding IBA
 molecular_functionGO:0004520 endodeoxyribonuclease activity IBA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0008094 DNA-dependent ATPase activity IBA


Pathways (from Reactome)
Pathway description
HDR through Homologous Recombination (HRR)
Resolution of D-loop Structures through Holliday Junction Intermediates
Homologous DNA Pairing and Strand Exchange
Presynaptic phase of homologous DNA pairing and strand exchange


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000026400 rad51d / RAD51 paralog D / O75771*  / complex / reaction






 

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