Manteia

ENSGALG00000033183

Gallus gallus

Features

Gene ID:	ENSGALG00000033183

Biological name :	GABRQ

Synonyms :	GABRQ / Gamma-aminobutyric acid receptor subunit beta-4 / P24045

Possible biological names infered from orthology :	Gamma-aminobutyric acid receptor subunit theta / gamma-aminobutyric acid type A receptor theta subunit / Q9JLF1 / Q9UN88

Species:	Gallus gallus

Chr. number:	4
Strand:	-1
Band:
Gene start:	10696144
Gene end:	10762914

Corresponding Affymetrix probe sets:	Gga.428.1.S1_at (Chicken Array)

Cross references:	Ensembl peptide - ENSGALP00000058040 NCBI entrez gene - 396288 See in Manteia. RefSeq - NM_001167704 RefSeq - NM_001167703 RefSeq Peptide - NP_001161175 RefSeq Peptide - NP_001161176 swissprot - P24045 Ensembl - ENSGALG00000033183

See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed

Ortholog prediction (from Ensembl)

Ortholog name	ID	Species
gabrb4	ENSDARG00000099096	Danio rerio
GABRQ	ENSG00000268089	Homo sapiens
Gabrq	ENSMUSG00000031344	Mus musculus

Paralog prediction (from Ensembl)

Paralog name	ID	Similarity(%)
GABRB3 / P19019 / Gamma-aminobutyric acid receptor subunit beta-3 / P63080* / P28472* / gamma-aminobutyric acid type A receptor beta3 subunit*	ENSGALG00000029392	70
GABRB2 / gamma-aminobutyric acid type A receptor beta2 subunit / P47870* / P63137* / Gamma-aminobutyric acid receptor subunit beta-2 *	ENSGALG00000001690	68
GABRP / gamma-aminobutyric acid type A receptor pi subunit / O00591* / Q8QZW7* / Gamma-aminobutyric acid receptor subunit pi *	ENSGALG00000002152	35
	ENSGALG00000031689	34
GABRD / gamma-aminobutyric acid type A receptor delta subunit / O14764* / P22933* / Gamma-aminobutyric acid receptor subunit delta *	ENSGALG00000001282	34
GABRR1 / gamma-aminobutyric acid type A receptor rho1 subunit / P24046* / P56475* / Gamma-aminobutyric acid receptor subunit rho-1 *	ENSGALG00000015778	33
GLRA2 / glycine receptor alpha 2 / P23416* / Q7TNC8* / Mus musculus glycine receptor, alpha 2 subunit (Glra2), transcript variant 3, mRNA.*	ENSGALG00000016571	33
GLRA4 / glycine receptor alpha 4 / Q5JXX5* / Q61603* / Glycine receptor subunit alpha-4 *	ENSGALG00000004936	33
GABRR2 / gamma-aminobutyric acid type A receptor rho2 subunit / P28476* / P56476* / Gamma-aminobutyric acid receptor subunit rho-2 *	ENSGALG00000015776	32
GABRR3 / gamma-aminobutyric acid type A receptor rho3 subunit (gene/pseudogene) / A8MPY1*	ENSGALG00000035787	32
GLRA3 / glycine receptor alpha 3 / O75311*	ENSGALG00000010781	32
GLRA1 / glycine receptor alpha 1 / P23415* / Q64018* / Glycine receptor subunit alpha-1 *	ENSGALG00000004134	31
GLRB / glycine receptor beta / P48167* / P48168* / Glycine receptor subunit beta *	ENSGALG00000009395	30

Protein motifs (from Interpro)

Interpro ID	Name
IPR002289	Gamma-aminobutyric-acid A receptor, beta subunit
IPR006028	Gamma-aminobutyric acid A receptor/Glycine receptor alpha
IPR006029	Neurotransmitter-gated ion-channel transmembrane domain
IPR006201	Neurotransmitter-gated ion-channel
IPR006202	Neurotransmitter-gated ion-channel ligand-binding domain
IPR018000	Neurotransmitter-gated ion-channel, conserved site

Gene Ontology (GO)

Type	GO ID	Term	Ev.Code
biological_process	GO:0006811	ion transport	IEA
biological_process	GO:0006821	chloride transport	IEA
biological_process	GO:0007165	signal transduction	IEA
biological_process	GO:0034220	ion transmembrane transport	IEA
biological_process	GO:1902476	chloride transmembrane transport	IEA
cellular_component	GO:0005886	plasma membrane	IEA
cellular_component	GO:0016020	membrane	IEA
cellular_component	GO:0016021	integral component of membrane	IEA
cellular_component	GO:0030054	cell junction	IEA
cellular_component	GO:0034707	chloride channel complex	IEA
cellular_component	GO:0045202	synapse	IEA
cellular_component	GO:0045211	postsynaptic membrane	IEA
cellular_component	GO:1902711	GABA-A receptor complex	IBA
molecular_function	GO:0004888	transmembrane signaling receptor activity	IEA
molecular_function	GO:0004890	GABA-A receptor activity	IBA
molecular_function	GO:0005216	ion channel activity	IEA
molecular_function	GO:0005230	extracellular ligand-gated ion channel activity	IEA
molecular_function	GO:0005254	chloride channel activity	IEA

Pathways (from Reactome)

Pathway description

GABA A receptor activation

Phenotype (from MGI, Zfin or HPO)

Phenotype

Definition

Genetic BG

No match

Interacting proteins (from Reactome)

Interactor ID	Name	Interaction type
ENSGALG00000001690	GABRB2 / gamma-aminobutyric acid type A receptor beta2 subunit / P47870* / P63137* / Gamma-aminobutyric acid receptor subunit beta-2 *	/ complex
ENSGALG00000038042	GABRG2 / P21548 / Gamma-aminobutyric acid receptor subunit gamma-2 / P22723* / P18507* / gamma-aminobutyric acid type A receptor gamma2 subunit*	/ complex
ENSGALG00000029392	GABRB3 / P19019 / Gamma-aminobutyric acid receptor subunit beta-3 / P63080* / P28472* / gamma-aminobutyric acid type A receptor beta3 subunit*	/ complex

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		© Olivier Tassy / Olivier Pourquie 2007-2024 contact: otassy@igbmc.fr