ENSGALG00000033234


Gallus gallus

Features
Gene ID: ENSGALG00000033234
  
Biological name :JAK3
  
Synonyms : JAK3 / tyrosine-protein kinase JAK3
  
Possible biological names infered from orthology : Janus kinase 3 / P52333
  
Species: Gallus gallus
  
Chr. number: 28
Strand: -1
Band:
Gene start: 3339736
Gene end: 3346314
  
Corresponding Affymetrix probe sets: Gga.4326.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000055747
NCBI entrez gene - 395845     See in Manteia.
RefSeq - NM_204996
RefSeq Peptide - NP_990327
swissprot - A0A1D5PS66
Ensembl - ENSGALG00000033234
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 jak3ENSDARG00000010252Danio rerio
 JAK3ENSG00000105639Homo sapiens
 Jak3ENSMUSG00000031805Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
JAK2 / Janus kinase 2 / O60674*ENSGALG0000001502748
JAK1 / tyrosine-protein kinase JAK1 / P23458* / Janus kinase 1*ENSGALG0000001103137


Protein motifs (from Interpro)
Interpro ID Name
 IPR000299  FERM domain
 IPR000719  Protein kinase domain
 IPR000980  SH2 domain
 IPR001245  Serine-threonine/tyrosine-protein kinase, catalytic domain
 IPR011009  Protein kinase-like domain superfamily
 IPR011993  PH-like domain superfamily
 IPR016251  Tyrosine-protein kinase, non-receptor Jak/Tyk2
 IPR017441  Protein kinase, ATP binding site
 IPR019749  Band 4.1 domain
 IPR020775  Tyrosine-protein kinase, non-receptor Jak3


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0018108 peptidyl-tyrosine phosphorylation IEA
 biological_processGO:0035556 intracellular signal transduction IEA
 biological_processGO:0035771 interleukin-4-mediated signaling pathway IEA
 biological_processGO:0070670 response to interleukin-4 IEA
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0016020 membrane IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0004713 protein tyrosine kinase activity IEA
 molecular_functionGO:0004715 non-membrane spanning protein tyrosine kinase activity IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0019903 protein phosphatase binding IEA


Pathways (from Reactome)
Pathway description
Interleukin-7 signaling
Interleukin-4 and Interleukin-13 signaling
Interleukin-20 family signaling
Interleukin-15 signaling
Interleukin-9 signaling
Interleukin-2 signaling
Interleukin-21 signaling


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000003282 STAT5B / signal transducer and activator of transcription 5B / P42229* / P42232* / P51692* / P42230* / STAT5A* / signal transducer and activator of transcription 5A*  / complex / reaction
 ENSGALG00000003267 STAT3 / Q6DV79 / Signal transducer and activator of transcription 3 / P40763* / P42227*  / reaction / complex
 ENSGALG00000007651 STAT1 / signal transducer and activator of transcription 1 / P42224*  / complex / reaction
 ENSGALG00000016564 PTK2B / protein tyrosine kinase 2 beta / Q14289* / Q9QVP9* / PTK2 protein tyrosine kinase 2 beta*  / reaction / complex
 ENSGALG00000011031 JAK1 / tyrosine-protein kinase JAK1 / P23458* / Janus kinase 1*  / complex
 ENSGALG00000015027 JAK2 / Janus kinase 2 / O60674*  / complex
 ENSGALG00000011844 IL21 / interleukin 21 / Q9ES17* / Q9HBE4*  / complex
 ENSGALG00000013372 IL7R / interleukin 7 receptor / P16871* / P16872* / Interleukin-7 receptor subunit alpha *  / complex
 ENSGALG00000033087 STAT4 / signal transducer and activator of transcription 4 / Q14765*  / complex






 

1 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr