ENSGALG00000035487


Gallus gallus

Features
Gene ID: ENSGALG00000035487
  
Biological name :SP1
  
Synonyms : SP1 / Sp1 transcription factor
  
Possible biological names infered from orthology : O89090 / P08047 / Transcription factor Sp1
  
Species: Gallus gallus
  
Chr. number: 33
Strand: 1
Band:
Gene start: 810188
Gene end: 827749
  
Corresponding Affymetrix probe sets: Gga.920.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000055178
Ensembl peptide - ENSGALP00000061868
Ensembl peptide - ENSGALP00000057803
Ensembl peptide - ENSGALP00000051805
NCBI entrez gene - 395303     See in Manteia.
RefSeq - NM_204604
RefSeq - XM_015300324
RefSeq Peptide - NP_989935
swissprot - A0A1D5PXV5
swissprot - A0A1D5PG84
swissprot - Q90WR9
Ensembl - ENSGALG00000035487
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 sp1ENSDARG00000088347Danio rerio
 SP1ENSG00000185591Homo sapiens
 Sp1ENSMUSG00000001280Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
SP3 / Q90WR8 / Transcription factor Sp3 / Q02447* / O70494* / Sp3 transcription factor*ENSGALG0000003179636
SP4 / Sp4 transcription factor / Q02446*ENSGALG0000003945436
SP2 / Sp2 transcription factor / Q02086*ENSGALG0000000023325
SP9 / Sp9 transcription factor / P0CG40* / Q64HY3* / Transcription factor Sp9 *ENSGALG0000004307918
SP8 / transcription factor Sp8 / Q8BMJ8* / Q8IXZ3* / Sp8 transcription factor*ENSGALG0000003572518
SP5 / transcription factor Sp5 / Q6BEB4* / Q9JHX2* / Sp5 transcription factor*ENSGALG0000003409417
KLF11 / Krueppel-like factor 11 / O14901* / Q8K1S5* / Kruppel like factor 11*ENSGALG0000001644016
KLF10 / Kruppel like factor 10 / O89091* / Q13118* / Mus musculus Kruppel-like factor 10 (Klf10), transcript variant 3, mRNA.*ENSGALG0000003791313
KLF9 / Kruppel like factor 9 / Q13886*ENSGALG000000273749
KLF13 / Kruppel like factor 13 / Q9JJZ6* / Q9Y2Y9* / Krueppel-like factor 13 *ENSGALG000000327486


Protein motifs (from Interpro)
Interpro ID Name
 IPR013087  Zinc finger C2H2-type


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006357 regulation of transcription by RNA polymerase II IEA
 biological_processGO:0010628 positive regulation of gene expression IEA
 biological_processGO:0043536 positive regulation of blood vessel endothelial cell migration IEA
 biological_processGO:0043923 positive regulation by host of viral transcription IEA
 biological_processGO:0045766 positive regulation of angiogenesis IEA
 biological_processGO:0045893 positive regulation of transcription, DNA-templated IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IEA
 biological_processGO:1904828 positive regulation of hydrogen sulfide biosynthetic process IEA
 biological_processGO:1905564 positive regulation of vascular endothelial cell proliferation IEA
 cellular_componentGO:0000790 nuclear chromatin IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0017053 transcriptional repressor complex IEA
 molecular_functionGO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding IEA
 molecular_functionGO:0000978 RNA polymerase II proximal promoter sequence-specific DNA binding IEA
 molecular_functionGO:0000982 transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding IEA
 molecular_functionGO:0001077 transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding IEA
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003690 double-stranded DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IEA
 molecular_functionGO:0008022 protein C-terminus binding IEA
 molecular_functionGO:0008134 transcription factor binding IEA
 molecular_functionGO:0042803 protein homodimerization activity IEA
 molecular_functionGO:0042826 histone deacetylase binding IEA
 molecular_functionGO:0043565 sequence-specific DNA binding IEA
 molecular_functionGO:0044212 transcription regulatory region DNA binding IEA
 molecular_functionGO:0070491 repressing transcription factor binding IEA
 molecular_functionGO:0071837 HMG box domain binding IEA


Pathways (from Reactome)
Pathway description
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
RNA polymerase II transcribes snRNA genes


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000014184 SMAD2* / Q15796* / Q62432* / SMAD family member 2* / Mothers against decapentaplegic homolog 2 *  / reaction / complex
 ENSGALG00000036001 SMAD2Z / SMAD2* / Q62432* / Q15796* / SMAD family member 2* / Mothers against decapentaplegic homolog 2 *  / reaction / complex






 

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