ENSGALG00000037148


Gallus gallus

Features
Gene ID: ENSGALG00000037148
  
Biological name :CRH
  
Synonyms : corticotropin releasing hormone / CRH
  
Possible biological names infered from orthology : Corticoliberin / P06850 / Q8CIT0
  
Species: Gallus gallus
  
Chr. number: 2
Strand: -1
Band:
Gene start: 115416217
Gene end: 115417210
  
Corresponding Affymetrix probe sets: Gga.11323.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000050250
NCBI entrez gene - 404297     See in Manteia.
RefSeq - NM_001123031
RefSeq Peptide - NP_001116503
swissprot - Q703P0
Ensembl - ENSGALG00000037148
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 crhaENSDARG00000093401Danio rerio
 crhbENSDARG00000027657Danio rerio
 CRHENSG00000147571Homo sapiens
 CrhENSMUSG00000049796Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000187  Corticotropin-releasing factor
 IPR003620  Urocortin/corticotropin-releasing factor
 IPR018446  Corticotropin-releasing factor conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001659 temperature homeostasis IDA
 biological_processGO:0001963 synaptic transmission, dopaminergic IEA
 biological_processGO:0006704 glucocorticoid biosynthetic process IEA
 biological_processGO:0006954 inflammatory response IEA
 biological_processGO:0007165 signal transduction IBA
 biological_processGO:0007565 female pregnancy IEA
 biological_processGO:0030324 lung development IEA
 biological_processGO:0030325 adrenal gland development IEA
 biological_processGO:0032099 negative regulation of appetite IMP
 biological_processGO:0032811 negative regulation of epinephrine secretion IBA
 biological_processGO:0035641 locomotory exploration behavior IEA
 biological_processGO:0051353 positive regulation of oxidoreductase activity IDA
 biological_processGO:0051461 positive regulation of corticotropin secretion IEA
 biological_processGO:0051464 positive regulation of cortisol secretion IEA
 biological_processGO:0070093 negative regulation of glucagon secretion IBA
 biological_processGO:0071625 vocalization behavior IDA
 biological_processGO:0072592 oxygen metabolic process TAS
 biological_processGO:0098869 cellular oxidant detoxification IEA
 biological_processGO:2000294 positive regulation of defecation IDA
 biological_processGO:2000310 regulation of NMDA receptor activity IEA
 biological_processGO:2000379 positive regulation of reactive oxygen species metabolic process TAS
 biological_processGO:2000852 regulation of corticosterone secretion IDA
 biological_processGO:2000854 positive regulation of corticosterone secretion IDA
 biological_processGO:2000985 positive regulation of ATP citrate synthase activity IDA
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005615 extracellular space IEA
 cellular_componentGO:0005737 cytoplasm IDA
 molecular_functionGO:0004601 peroxidase activity IDA
 molecular_functionGO:0005179 hormone activity IEA
 molecular_functionGO:0005184 neuropeptide hormone activity IBA
 molecular_functionGO:0017045 corticotropin-releasing hormone activity IMP


Pathways (from Reactome)
Pathway description
Class B/2 (Secretin family receptors)
G alpha (s) signalling events


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000014994 CRHBP / corticotropin releasing hormone binding protein / P24387* / Q60571* / Corticotropin-releasing factor-binding protein *  / complex / reaction






 

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