ENSGALG00000037220


Gallus gallus

Features
Gene ID: ENSGALG00000037220
  
Biological name :ASTL
  
Synonyms : Astacin-like metalloendopeptidase / ASTL / P0DJJ2
  
Possible biological names infered from orthology : Q6HA08 / Q6HA09
  
Species: Gallus gallus
  
Chr. number: 5
Strand: 1
Band:
Gene start: 22351047
Gene end: 22362930
  
Corresponding Affymetrix probe sets: GgaAffx.5056.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000052553
Ensembl peptide - ENSGALP00000046927
NCBI entrez gene - 423176     See in Manteia.
RefSeq - NM_001305090
RefSeq Peptide - NP_001292019
swissprot - P0DJJ2
swissprot - A0A1D5PIC0
Ensembl - ENSGALG00000037220
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 si:ch211-167j6.4ENSDARG00000070011Danio rerio
 si:ch211-167j6.5ENSDARG00000058409Danio rerio
 ASTLENSG00000188886Homo sapiens
 AstlENSMUSG00000050468Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ASTL* / Q6HA08* / Q6HA09* / astacin like metalloendopeptidase*ENSGALG0000004398443
MEP1B / meprin A subunit beta / Q16820* / Q61847*ENSGALG0000004460627
MEP1A / meprin A subunit alpha / P28825* / Q16819*ENSGALG0000003303326


Protein motifs (from Interpro)
Interpro ID Name
 IPR000859  CUB domain
 IPR001506  Peptidase M12A
 IPR006026  Peptidase, metallopeptidase
 IPR017370  Hatching enzyme, Uvs2
 IPR024079  Metallopeptidase, catalytic domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006508 proteolysis IEA
 biological_processGO:0007155 cell adhesion ISS
 biological_processGO:0007338 single fertilization IEA
 biological_processGO:0009566 fertilization ISS
 biological_processGO:0010954 positive regulation of protein processing ISS
 biological_processGO:0060468 prevention of polyspermy ISS
 biological_processGO:2000360 negative regulation of binding of sperm to zona pellucida ISS
 cellular_componentGO:0005737 cytoplasm ISS
 cellular_componentGO:0005886 plasma membrane ISS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0030133 transport vesicle IEA
 cellular_componentGO:0031410 cytoplasmic vesicle IEA
 cellular_componentGO:0060473 cortical granule ISS
 molecular_functionGO:0004222 metalloendopeptidase activity IEA
 molecular_functionGO:0008233 peptidase activity IEA
 molecular_functionGO:0008237 metallopeptidase activity IEA
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0070001 aspartic-type peptidase activity ISS
 molecular_functionGO:0070002 glutamic-type peptidase activity ISS


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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