ENSGALG00000037402


Gallus gallus

Features
Gene ID: ENSGALG00000037402
  
Biological name :CTGF
  
Synonyms : connective tissue growth factor / CTGF
  
Possible biological names infered from orthology : P29268 / P29279
  
Species: Gallus gallus
  
Chr. number: 3
Strand: 1
Band:
Gene start: 57348864
Gene end: 57352201
  
Corresponding Affymetrix probe sets: Gga.4051.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000047058
Ensembl peptide - ENSGALP00000056940
Ensembl peptide - ENSGALP00000050646
NCBI entrez gene - 374135     See in Manteia.
RefSeq - NM_204274
RefSeq Peptide - NP_989605
swissprot - A0A1D5PVH1
swissprot - A0A1D5PD05
swissprot - Q98TQ8
Ensembl - ENSGALG00000037402
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ctgfaENSDARG00000042934Danio rerio
 CTGFENSG00000118523Homo sapiens
 CtgfENSMUSG00000019997Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ENSGALG0000003475659
NOV / protein NOV precursor / P48745* / Q64299* / nephroblastoma overexpressed*ENSGALG0000003836452
CYR61 / P19336 / Protein CYR61 / O00622* / P18406* / cysteine rich angiogenic inducer 61*ENSGALG0000000866148
WISP1 / WNT1-inducible-signaling pathway protein 1 precursor / O54775* / O95388* / WNT1 inducible signaling pathway protein 1*ENSGALG0000003011545
WISP2 / WNT1 inducible signaling pathway protein 2 / O76076*ENSGALG0000000415434
WISP3* / D3Z5L9* / O95389* / WNT1 inducible signaling pathway protein 3*ENSGALG0000001993415


Protein motifs (from Interpro)
Interpro ID Name
 IPR000867  Insulin-like growth factor-binding protein, IGFBP
 IPR000884  Thrombospondin type-1 (TSP1) repeat
 IPR001007  VWFC domain
 IPR006207  Cystine knot, C-terminal
 IPR006208  Glycoprotein hormone subunit beta
 IPR009030  Growth factor receptor cysteine-rich domain superfamily
 IPR012395  IGFBP-related, CNN
 IPR017891  Insulin-like growth factor binding protein, N-terminal, Cys-rich conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001502 cartilage condensation IEA
 biological_processGO:0001503 ossification IEA
 biological_processGO:0001525 angiogenesis IEA
 biological_processGO:0001558 regulation of cell growth IEA
 biological_processGO:0001894 tissue homeostasis IEA
 biological_processGO:0007155 cell adhesion IBA
 biological_processGO:0007160 cell-matrix adhesion IEA
 biological_processGO:0007165 signal transduction IBA
 biological_processGO:0007229 integrin-mediated signaling pathway IEA
 biological_processGO:0007267 cell-cell signaling IBA
 biological_processGO:0008543 fibroblast growth factor receptor signaling pathway IEA
 biological_processGO:0010629 negative regulation of gene expression IEA
 biological_processGO:0016477 cell migration IEA
 biological_processGO:0030154 cell differentiation IEA
 biological_processGO:0030324 lung development IEA
 biological_processGO:0032330 regulation of chondrocyte differentiation IEA
 biological_processGO:0035988 chondrocyte proliferation IEA
 biological_processGO:0045597 positive regulation of cell differentiation IEA
 biological_processGO:0046330 positive regulation of JNK cascade IEA
 biological_processGO:0051496 positive regulation of stress fiber assembly IEA
 biological_processGO:0060548 negative regulation of cell death IBA
 biological_processGO:0061448 connective tissue development IEA
 biological_processGO:0070374 positive regulation of ERK1 and ERK2 cascade IEA
 biological_processGO:0072593 reactive oxygen species metabolic process IEA
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005615 extracellular space IEA
 molecular_functionGO:0005178 integrin binding IEA
 molecular_functionGO:0005520 insulin-like growth factor binding IEA
 molecular_functionGO:0008022 protein C-terminus binding IEA
 molecular_functionGO:0008201 heparin binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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