ENSGALG00000008661


Gallus gallus

Features
Gene ID: ENSGALG00000008661
  
Biological name :CYR61
  
Synonyms : CYR61 / P19336 / Protein CYR61
  
Possible biological names infered from orthology : cysteine rich angiogenic inducer 61 / O00622 / P18406
  
Species: Gallus gallus
  
Chr. number: 8
Strand: -1
Band:
Gene start: 16258746
Gene end: 16261197
  
Corresponding Affymetrix probe sets: Gga.2200.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000014090
NCBI entrez gene - 429089     See in Manteia.
RefSeq - NM_001031563
RefSeq Peptide - NP_001026734
swissprot - F1NKG6
swissprot - P19336
Ensembl - ENSGALG00000008661
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 cyr61ENSDARG00000023062Danio rerio
 CYR61ENSG00000142871Homo sapiens
 Cyr61ENSMUSG00000028195Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ENSGALG0000003475644
CTGF / connective tissue growth factor / P29268* / P29279*ENSGALG0000003740244
NOV / protein NOV precursor / P48745* / Q64299* / nephroblastoma overexpressed*ENSGALG0000003836443
WISP1 / WNT1-inducible-signaling pathway protein 1 precursor / O54775* / O95388* / WNT1 inducible signaling pathway protein 1*ENSGALG0000003011537
WISP2 / WNT1 inducible signaling pathway protein 2 / O76076*ENSGALG0000000415426
WISP3* / D3Z5L9* / O95389* / WNT1 inducible signaling pathway protein 3*ENSGALG0000001993412


Protein motifs (from Interpro)
Interpro ID Name
 IPR000867  Insulin-like growth factor-binding protein, IGFBP
 IPR000884  Thrombospondin type-1 (TSP1) repeat
 IPR001007  VWFC domain
 IPR006207  Cystine knot, C-terminal
 IPR006208  Glycoprotein hormone subunit beta
 IPR009030  Growth factor receptor cysteine-rich domain superfamily
 IPR012395  IGFBP-related, CNN
 IPR017891  Insulin-like growth factor binding protein, N-terminal, Cys-rich conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001558 regulation of cell growth IEA
 biological_processGO:0001649 osteoblast differentiation IEA
 biological_processGO:0001934 positive regulation of protein phosphorylation IEA
 biological_processGO:0002041 intussusceptive angiogenesis IEA
 biological_processGO:0003181 atrioventricular valve morphogenesis IEA
 biological_processGO:0003278 apoptotic process involved in heart morphogenesis IEA
 biological_processGO:0003281 ventricular septum development IEA
 biological_processGO:0007155 cell adhesion IEA
 biological_processGO:0007165 signal transduction IBA
 biological_processGO:0007267 cell-cell signaling IBA
 biological_processGO:0010518 positive regulation of phospholipase activity IEA
 biological_processGO:0010811 positive regulation of cell-substrate adhesion IEA
 biological_processGO:0030198 extracellular matrix organization IEA
 biological_processGO:0030335 positive regulation of cell migration IEA
 biological_processGO:0030513 positive regulation of BMP signaling pathway IEA
 biological_processGO:0033690 positive regulation of osteoblast proliferation IEA
 biological_processGO:0043065 positive regulation of apoptotic process IEA
 biological_processGO:0043066 negative regulation of apoptotic process IEA
 biological_processGO:0043280 positive regulation of cysteine-type endopeptidase activity involved in apoptotic process IEA
 biological_processGO:0044319 wound healing, spreading of cells IEA
 biological_processGO:0045597 positive regulation of cell differentiation IEA
 biological_processGO:0045669 positive regulation of osteoblast differentiation IEA
 biological_processGO:0045860 positive regulation of protein kinase activity IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IEA
 biological_processGO:0060413 atrial septum morphogenesis IEA
 biological_processGO:0060548 negative regulation of cell death IBA
 biological_processGO:0060591 chondroblast differentiation IEA
 biological_processGO:0060710 chorio-allantoic fusion IEA
 biological_processGO:0060716 labyrinthine layer blood vessel development IEA
 biological_processGO:0061036 positive regulation of cartilage development IEA
 biological_processGO:0070372 regulation of ERK1 and ERK2 cascade IEA
 biological_processGO:0072593 reactive oxygen species metabolic process IEA
 biological_processGO:0098609 cell-cell adhesion IEA
 biological_processGO:2000304 positive regulation of ceramide biosynthetic process IEA
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005615 extracellular space IEA
 molecular_functionGO:0005178 integrin binding IEA
 molecular_functionGO:0005520 insulin-like growth factor binding IEA
 molecular_functionGO:0008201 heparin binding IBA
 molecular_functionGO:0019838 growth factor binding IEA
 molecular_functionGO:0050840 extracellular matrix binding IEA


Pathways (from Reactome)
Pathway description
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)
Post-translational protein phosphorylation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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