ENSGALG00000037603


Gallus gallus

Features
Gene ID: ENSGALG00000037603
  
Biological name :SESN2
  
Synonyms : SESN2 / sestrin 2
  
Possible biological names infered from orthology : P58004 / P58043
  
Species: Gallus gallus
  
Chr. number: 23
Strand: 1
Band:
Gene start: 2099731
Gene end: 2105548
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSGALP00000053267
NCBI entrez gene - 100858796     See in Manteia.
RefSeq - XM_015297707
swissprot - A0A1D5PKB0
Ensembl - ENSGALG00000037603
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 sesn2ENSDARG00000070012Danio rerio
 SESN2ENSG00000130766Homo sapiens
 Sesn2ENSMUSG00000028893Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
SESN1 / sestrin 1 / P58006* / Q9Y6P5*ENSGALG0000001528655
SESN3* / P58005* / Q9CYP7* / sestrin 3*ENSGALG0000001720453
ENSGALG0000000564839


Protein motifs (from Interpro)
Interpro ID Name
 IPR006730  Sestrin


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001932 regulation of protein phosphorylation IEA
 biological_processGO:0006635 fatty acid beta-oxidation IEA
 biological_processGO:0007005 mitochondrion organization IEA
 biological_processGO:0009749 response to glucose IEA
 biological_processGO:0016239 positive regulation of macroautophagy IEA
 biological_processGO:0030308 negative regulation of cell growth IEA
 biological_processGO:0030330 DNA damage response, signal transduction by p53 class mediator IEA
 biological_processGO:0032042 mitochondrial DNA metabolic process IEA
 biological_processGO:0032868 response to insulin IEA
 biological_processGO:0034198 cellular response to amino acid starvation IEA
 biological_processGO:0034599 cellular response to oxidative stress IEA
 biological_processGO:0036091 positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress IEA
 biological_processGO:0042149 cellular response to glucose starvation IEA
 biological_processGO:0042593 glucose homeostasis IEA
 biological_processGO:0043491 protein kinase B signaling IEA
 biological_processGO:0046323 glucose import IEA
 biological_processGO:0070328 triglyceride homeostasis IEA
 biological_processGO:0071230 cellular response to amino acid stimulus IEA
 biological_processGO:0071233 cellular response to leucine IEA
 biological_processGO:0072593 reactive oxygen species metabolic process IEA
 biological_processGO:0098869 cellular oxidant detoxification IEA
 biological_processGO:1900182 positive regulation of protein localization to nucleus IEA
 biological_processGO:1901031 regulation of response to reactive oxygen species IEA
 biological_processGO:1902010 negative regulation of translation in response to endoplasmic reticulum stress IEA
 biological_processGO:1904262 negative regulation of TORC1 signaling IEA
 biological_processGO:1904504 positive regulation of lipophagy IEA
 biological_processGO:1990253 cellular response to leucine starvation IEA
 biological_processGO:2000479 regulation of cAMP-dependent protein kinase activity IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0031588 nucleotide-activated protein kinase complex IEA
 cellular_componentGO:0031932 TORC2 complex IEA
 cellular_componentGO:0061700 GATOR2 complex IEA
 cellular_componentGO:1990316 Atg1/ULK1 kinase complex IEA
 molecular_functionGO:0005092 GDP-dissociation inhibitor activity IEA
 molecular_functionGO:0016684 oxidoreductase activity, acting on peroxide as acceptor IEA
 molecular_functionGO:0032542 sulfiredoxin activity IEA
 molecular_functionGO:0070728 leucine binding IEA


Pathways (from Reactome)
Pathway description
TP53 Regulates Metabolic Genes


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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