ENSGALG00000039424


Gallus gallus

Features
Gene ID: ENSGALG00000039424
  
Biological name :MTRR
  
Synonyms : 5-methyltetrahydrofolate-homocysteine methyltransferase reductase / MTRR
  
Possible biological names infered from orthology : Q9UBK8
  
Species: Gallus gallus
  
Chr. number: 2
Strand: -1
Band:
Gene start: 79446863
Gene end: 79471101
  
Corresponding Affymetrix probe sets: Gga.10838.1.S1_s_at (Chicken Array)   GgaAffx.24101.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000054731
NCBI entrez gene - 428502     See in Manteia.
RefSeq - XM_004935129
RefSeq - XM_426057
swissprot - A0A1D5PPD2
Ensembl - ENSGALG00000039424
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 mtrrENSDARG00000045398Danio rerio
 MTRRENSG00000124275Homo sapiens
 MtrrENSMUSG00000034617Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
NDOR1 / NADPH dependent diflavin oxidoreductase 1 / A2AI05* / Q9UHB4* / AL732309.2*ENSGALG0000000892024


Protein motifs (from Interpro)
Interpro ID Name
 IPR001094  Flavodoxin-like
 IPR001433  Oxidoreductase FAD/NAD(P)-binding
 IPR001709  Flavoprotein pyridine nucleotide cytochrome reductase
 IPR003097  FAD-binding, type 1
 IPR008254  Flavodoxin/nitric oxide synthase
 IPR017927  Ferredoxin reductase-type FAD-binding domain
 IPR017938  Riboflavin synthase-like beta-barrel
 IPR023173  NADPH-cytochrome p450 reductase, FAD-binding, alpha-helical domain superfamily
 IPR029039  Flavoprotein-like superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0009086 methionine biosynthetic process IEA
 biological_processGO:0043418 homocysteine catabolic process IEA
 biological_processGO:0046655 folic acid metabolic process IEA
 biological_processGO:0055114 oxidation-reduction process IEA
 biological_processGO:1904042 negative regulation of cystathionine beta-synthase activity IEA
 molecular_functionGO:0003958 NADPH-hemoprotein reductase activity IEA
 molecular_functionGO:0010181 FMN binding IEA
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0016723 oxidoreductase activity, oxidizing metal ions, NAD or NADP as acceptor IEA
 molecular_functionGO:0030586 [methionine synthase] reductase activity IEA
 molecular_functionGO:0050444 aquacobalamin reductase (NADPH) activity IEA
 molecular_functionGO:0050660 flavin adenine dinucleotide binding IEA
 molecular_functionGO:0070402 NADPH binding IEA
 molecular_functionGO:0071949 FAD binding IEA


Pathways (from Reactome)
Pathway description
Methylation
Sulfur amino acid metabolism
Cobalamin (Cbl, vitamin B12) transport and metabolism


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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