ENSGALG00000039434


Gallus gallus

Features
Gene ID: ENSGALG00000039434
  
Biological name :PIAS2
  
Synonyms : PIAS2 / protein inhibitor of activated STAT 2
  
Possible biological names infered from orthology : E3 SUMO-protein ligase PIAS2 / O75928 / Q8C5D8
  
Species: Gallus gallus
  
Chr. number: Z
Strand: 1
Band:
Gene start: 1785399
Gene end: 1812739
  
Corresponding Affymetrix probe sets: Gga.7798.1.S1_at (Chicken Array)   GgaAffx.1212.1.S1_s_at (Chicken Array)   GgaAffx.12853.1.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000049443
Ensembl peptide - ENSGALP00000047788
NCBI entrez gene - 416383     See in Manteia.
RefSeq - XM_015277284
RefSeq - NM_001030626
RefSeq - XM_015277281
RefSeq - XM_015277282
RefSeq - XM_015277283
RefSeq - XM_015277280
RefSeq Peptide - NP_001025797
swissprot - Q5ZIN4
swissprot - A0A1D5P523
Ensembl - ENSGALG00000039434
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 pias2ENSDARG00000092979Danio rerio
 PIAS2ENSG00000078043Homo sapiens
 Pias2ENSMUSG00000025423Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
PIAS1 / E3 SUMO-protein ligase PIAS1 / O75925* / O88907* / protein inhibitor of activated STAT 1*ENSGALG0000000797056
PIAS4 / protein inhibitor of activated STAT 4 / Q8N2W9* / Q9JM05*ENSGALG0000003441338
PIAS3* / O54714* / Q9Y6X2* / E3 SUMO-protein ligase PIAS3 * / protein inhibitor of activated STAT 3*ENSGALG0000003404235
ZMIZ1 / zinc finger MIZ-type containing 1 / Q6P1E1* / Q9ULJ6*ENSGALG0000000485020


Protein motifs (from Interpro)
Interpro ID Name
 IPR003034  SAP domain
 IPR004181  Zinc finger, MIZ-type
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR023321  PINIT domain
 IPR027228  E3 SUMO-protein ligase PIAS2


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006357 regulation of transcription by RNA polymerase II IEA
 biological_processGO:0016925 protein sumoylation IEA
 biological_processGO:0045667 regulation of osteoblast differentiation IEA
 biological_processGO:0045893 positive regulation of transcription, DNA-templated IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IEA
 biological_processGO:0060766 negative regulation of androgen receptor signaling pathway IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0016604 nuclear body IEA
 cellular_componentGO:0016605 PML body IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0008134 transcription factor binding IEA
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0019789 SUMO transferase activity IEA
 molecular_functionGO:0031625 ubiquitin protein ligase binding IEA
 molecular_functionGO:0061665 SUMO ligase activity IEA


Pathways (from Reactome)
Pathway description
SUMOylation of DNA damage response and repair proteins
SUMOylation of transcription factors
SUMOylation of ubiquitinylation proteins
SUMOylation of transcription cofactors
SUMOylation of intracellular receptors
SUMOylation of chromatin organization proteins


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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