ENSGALG00000039528


Gallus gallus

Features
Gene ID: ENSGALG00000039528
  
Biological name :
  
Synonyms :
  
Possible biological names infered from orthology : 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1 / phospholipase C epsilon 1 / PLCE1 / Q8K4S1 / Q9P212
  
Species: Gallus gallus
  
Chr. number: 6
Strand: -1
Band:
Gene start: 20124539
Gene end: 20190565
  
Corresponding Affymetrix probe sets: Gga.5560.2.A1_at (Chicken Array)   GgaAffx.4095.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000055018
NCBI entrez gene - 425224     See in Manteia.
RefSeq - XM_015288858
swissprot - A0A1D5PQ57
Ensembl - ENSGALG00000039528
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 plce1ENSDARG00000087921Danio rerio
 PLCE1ENSG00000138193Homo sapiens
 Plce1ENSMUSG00000024998Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
PLCG1 / phospholipase C gamma 1 / P19174* / Q62077* / 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 *ENSGALG0000000375017
ENSGALG0000003608516
PLCG2 / phospholipase C gamma 2 / P16885* / Q8CIH5* / 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 *ENSGALG0000003350716
PLCE1* / Q8K4S1* / Q9P212* / phospholipase C epsilon 1* / 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1 *ENSGALG000000407991


Protein motifs (from Interpro)
Interpro ID Name
 IPR000909  Phosphatidylinositol-specific phospholipase C, X domain
 IPR001192  Phosphoinositide phospholipase C family
 IPR001895  Ras guanine-nucleotide exchange factors catalytic domain
 IPR011992  EF-hand domain pair
 IPR011993  PH-like domain superfamily
 IPR015359  Phosphoinositide-specific phospholipase C, EF-hand-like domain
 IPR017946  PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily
 IPR023578  Ras guanine nucleotide exchange factor domain superfamily
 IPR028398  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006629 lipid metabolic process IEA
 biological_processGO:0007264 small GTPase mediated signal transduction IEA
 biological_processGO:0016042 lipid catabolic process IEA
 biological_processGO:0035556 intracellular signal transduction IEA
 biological_processGO:0065009 regulation of molecular function IEA
 cellular_componentGO:0005622 intracellular IEA
 molecular_functionGO:0004435 phosphatidylinositol phospholipase C activity IEA
 molecular_functionGO:0005085 guanyl-nucleotide exchange factor activity IEA
 molecular_functionGO:0008081 phosphoric diester hydrolase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA


Pathways (from Reactome)
Pathway description
Synthesis of IP3 and IP4 in the cytosol


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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