ENSGALG00000040373


Gallus gallus

Features
Gene ID: ENSGALG00000040373
  
Biological name :EXOSC2
  
Synonyms : EXOSC2 / exosome complex component RRP4
  
Possible biological names infered from orthology : exosome component 2 / Q13868 / Q8VBV3
  
Species: Gallus gallus
  
Chr. number: 17
Strand: 1
Band:
Gene start: 6429083
Gene end: 6433587
  
Corresponding Affymetrix probe sets: Gga.12684.1.S1_s_at (Chicken Array)   Gga.12684.2.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000058592
Ensembl peptide - ENSGALP00000064384
Ensembl peptide - ENSGALP00000061756
NCBI entrez gene - 417182     See in Manteia.
RefSeq - NM_001012798
RefSeq Peptide - NP_001012816
swissprot - A0A1L1RZU7
swissprot - A0A1L1RSH0
swissprot - A0A1D5Q022
Ensembl - ENSGALG00000040373
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 exosc2ENSDARG00000028688Danio rerio
 EXOSC2ENSG00000130713Homo sapiens
 Exosc2ENSMUSG00000039356Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR004088  K Homology domain, type 1
 IPR012340  Nucleic acid-binding, OB-fold
 IPR022967  RNA-binding domain, S1
 IPR025721  Exosome complex component, N-terminal domain
 IPR026699  Exosome complex RNA-binding protein 1/RRP40/RRP4


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0030307 positive regulation of cell growth IEA
 cellular_componentGO:0000178 exosome (RNase complex) IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005730 nucleolus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 molecular_functionGO:0003723 RNA binding IEA


Pathways (from Reactome)
Pathway description
mRNA decay by 3 to 5 exoribonuclease
Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA
KSRP (KHSRP) binds and destabilizes mRNA
Major pathway of rRNA processing in the nucleolus and cytosol


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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contact: otassy@igbmc.fr