ENSGALG00000040755


Gallus gallus

Features
Gene ID: ENSGALG00000040755
  
Biological name :ANGPT4
  
Synonyms : angiopoietin 4 / ANGPT4
  
Possible biological names infered from orthology : Q9WVH6 / Q9Y264
  
Species: Gallus gallus
  
Chr. number: 20
Strand: 1
Band:
Gene start: 10094792
Gene end: 10101201
  
Corresponding Affymetrix probe sets: Gga.7236.1.S1_at (Chicken Array)   GgaAffx.11196.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000058314
NCBI entrez gene - 771763     See in Manteia.
RefSeq - XM_001235002
swissprot - A0A1D5PZA4
Ensembl - ENSGALG00000040755
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 angpt4ENSDARG00000076787Danio rerio
 ANGPT4ENSG00000101280Homo sapiens
 Angpt4ENSMUSG00000027460Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ANGPT1 / angiopoietin 1 / O08538* / Q15389*ENSGALG0000002998356
ANGPT2 / angiopoietin-2 / O15123* / O35608*ENSGALG0000003618946
ANGPTL1 / angiopoietin like 1 / O95841* / Q640P2* / Angiopoietin-related protein 1 *ENSGALG0000000429027
ANGPTL2 / angiopoietin like 2 / Q9R045* / Q9UKU9* / Angiopoietin-related protein 2 *ENSGALG0000000092726
FGL2 / fibrinogen like 2 / P12804* / Q14314* / Fibroleukin *ENSGALG0000000830626
ANGPTL7 / angiopoietin like 7 / O43827* / Q8R1Q3* / Angiopoietin-related protein 7 *ENSGALG0000000317924
FIBCD1 / fibrinogen C domain containing 1 / A2AV25* / Q8N539* / Fibrinogen C domain-containing protein 1 *ENSGALG0000000386621
FCN1* / FCN2* / Fcna* / Fcnb* / Q15485* / O70165* / O70497* / O00602* / ficolin 2* / ficolin 1*ENSGALG0000004077120
ENSGALG0000001659919


Protein motifs (from Interpro)
Interpro ID Name
 IPR002181  Fibrinogen, alpha/beta/gamma chain, C-terminal globular domain
 IPR014715  Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 2
 IPR014716  Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 1
 IPR020837  Fibrinogen, conserved site
 IPR028845  Angiopoietin-4


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001525 angiogenesis IEA
 biological_processGO:0007219 Notch signaling pathway IEA
 biological_processGO:0010595 positive regulation of endothelial cell migration IEA
 biological_processGO:0016525 negative regulation of angiogenesis IEA
 biological_processGO:0043066 negative regulation of apoptotic process IEA
 biological_processGO:0043536 positive regulation of blood vessel endothelial cell migration IEA
 biological_processGO:0043537 negative regulation of blood vessel endothelial cell migration IEA
 biological_processGO:0045766 positive regulation of angiogenesis IEA
 biological_processGO:0050731 positive regulation of peptidyl-tyrosine phosphorylation IEA
 biological_processGO:0071456 cellular response to hypoxia IEA
 cellular_componentGO:0005615 extracellular space IEA
 molecular_functionGO:0030297 transmembrane receptor protein tyrosine kinase activator activity IEA
 molecular_functionGO:0030971 receptor tyrosine kinase binding IEA


Pathways (from Reactome)
Pathway description
Tie2 Signaling


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000001840 TEK / TEK receptor tyrosine kinase / Q02763* / Q02858*  / reaction / complex






 

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contact: otassy@igbmc.fr