ENSGALG00000041102


Gallus gallus

Features
Gene ID: ENSGALG00000041102
  
Biological name :CDK5RAP2
  
Synonyms : CDK5RAP2 / CDK5 regulatory subunit associated protein 2
  
Possible biological names infered from orthology : Q8K389 / Q96SN8
  
Species: Gallus gallus
  
Chr. number: 17
Strand: -1
Band:
Gene start: 5006022
Gene end: 5105974
  
Corresponding Affymetrix probe sets: Gga.12425.1.S1_at (Chicken Array)   Gga.17595.1.S1_at (Chicken Array)   GgaAffx.22113.1.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000044809
Ensembl peptide - ENSGALP00000052204
Ensembl peptide - ENSGALP00000050074
Ensembl peptide - ENSGALP00000043857
NCBI entrez gene - 771445     See in Manteia.
RefSeq - XM_004945806
RefSeq - XM_015279696
RefSeq - XM_015279697
swissprot - A0A1D5NWR7
swissprot - A0A1D5NU48
Ensembl - ENSGALG00000041102
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 zgc:55582ENSDARG00000024219Danio rerio
 Q96SN8ENSG00000136861Homo sapiens
 Q8K389ENSMUSG00000039298Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q5VU43* / Q80YT7* / PDE4DIP* / phosphodiesterase 4D interacting protein* / phosphodiesterase 4D interacting protein (myomegalin)*ENSGALG000000367836


Protein motifs (from Interpro)
Interpro ID Name
 IPR012943  Centrosomin, N-terminal motif 1


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000132 establishment of mitotic spindle orientation IEA
 biological_processGO:0000226 microtubule cytoskeleton organization IEA
 biological_processGO:0001578 microtubule bundle formation IEA
 biological_processGO:0007059 chromosome segregation IEA
 biological_processGO:0007098 centrosome cycle IEA
 biological_processGO:0007099 centriole replication IEA
 biological_processGO:0007420 brain development IEA
 biological_processGO:0022008 neurogenesis IEA
 biological_processGO:0031023 microtubule organizing center organization IEA
 biological_processGO:0031116 positive regulation of microtubule polymerization IEA
 biological_processGO:0045665 negative regulation of neuron differentiation IEA
 biological_processGO:0045893 positive regulation of transcription, DNA-templated IEA
 biological_processGO:0046600 negative regulation of centriole replication IEA
 biological_processGO:0090266 regulation of mitotic cell cycle spindle assembly checkpoint IEA
 cellular_componentGO:0000242 pericentriolar material IEA
 cellular_componentGO:0000922 spindle pole IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0005813 centrosome IEA
 cellular_componentGO:0005815 microtubule organizing center IEA
 cellular_componentGO:0005874 microtubule IEA
 cellular_componentGO:0008274 gamma-tubulin ring complex IEA
 cellular_componentGO:0030054 cell junction IEA
 cellular_componentGO:0035371 microtubule plus-end IEA
 cellular_componentGO:0048471 perinuclear region of cytoplasm IEA
 cellular_componentGO:0097431 mitotic spindle pole IEA
 molecular_functionGO:0005516 calmodulin binding IEA
 molecular_functionGO:0008017 microtubule binding IEA
 molecular_functionGO:0015631 tubulin binding IEA
 molecular_functionGO:0019901 protein kinase binding IEA
 molecular_functionGO:0043015 gamma-tubulin binding IEA
 molecular_functionGO:0044212 transcription regulatory region DNA binding IEA


Pathways (from Reactome)
Pathway description
Regulation of PLK1 Activity at G2/M Transition
Loss of Nlp from mitotic centrosomes
Recruitment of mitotic centrosome proteins and complexes
Loss of proteins required for interphase microtubule organization from the centrosome
Recruitment of NuMA to mitotic centrosomes
Anchoring of the basal body to the plasma membrane
AURKA Activation by TPX2


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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