ENSGALG00000042077


Gallus gallus

Features
Gene ID: ENSGALG00000042077
  
Biological name :HIC1
  
Synonyms : HIC1 / hypermethylated in cancer 1 protein
  
Possible biological names infered from orthology : HIC ZBTB transcriptional repressor 1 / Q14526
  
Species: Gallus gallus
  
Chr. number: 19
Strand: 1
Band:
Gene start: 5521562
Gene end: 5525889
  
Corresponding Affymetrix probe sets: Gga.3731.2.S1_a_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000053534
NCBI entrez gene - 396164     See in Manteia.
RefSeq - NM_205236
RefSeq - XM_015295680
RefSeq Peptide - NP_990567
swissprot - A0A1D5PL20
Ensembl - ENSGALG00000042077
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 hic1ENSDARG00000055493Danio rerio
 HIC1ENSG00000177374Homo sapiens
 Hic1ENSMUSG00000043099Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
HIC2 / HIC ZBTB transcriptional repressor 2 / Q96JB3* / Q9JLZ6* / Hypermethylated in cancer 2 protein *ENSGALG0000003341640
ZBTB18 / zinc finger and BTB domain containing 18 / Q99592* / Q9WUK6*ENSGALG0000001070517
ENSGALG0000002302516
ZBTB7C / zinc finger and BTB domain containing 7C / A1YPR0* / Q8VCZ7*ENSGALG0000003340816
ZBTB5 / zinc finger and BTB domain containing 5 / O15062* / Q7TQG0*ENSGALG0000000535415
ZBTB7A / O93567 / Zinc finger and BTB domain-containing protein 7A / O95365* / O88939* / zinc finger and BTB domain containing 7A*ENSGALG0000002590715
ZBTB46 / zinc finger and BTB domain containing 46 / Q86UZ6* / Q8BID6*ENSGALG0000000606215
ZBTB8A / zinc finger and BTB domain containing 8A / Q96BR9* / Q9CWH1*ENSGALG0000003889614
O15156* / Q64321* / ZBTB7B* / zinc finger and BTB domain containing 7B*ENSGALG0000004148413
ZBTB10 / zinc finger and BTB domain containing 10 / Q96DT7*ENSGALG0000003437610
ZBTB8B / zinc finger and BTB domain-containing protein 8B / Q8NAP8* / AL033529.1* / zinc finger and BTB domain containing 8B*ENSGALG000000034089
Q8NAP8* / ZBTB8B* / AL033529.1* / zinc finger and BTB domain containing 8B*ENSGALG000000034209
Q8NAP8* / ZBTB8B* / AL033529.1* / zinc finger and BTB domain containing 8B*ENSGALG000000362151


Protein motifs (from Interpro)
Interpro ID Name
 IPR000210  BTB/POZ domain
 IPR011333  SKP1/BTB/POZ domain superfamily
 IPR013087  Zinc finger C2H2-type
 IPR028424  Hypermethylated in cancer 1 protein


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IEA
 biological_processGO:0008630 intrinsic apoptotic signaling pathway in response to DNA damage IEA
 biological_processGO:0030178 negative regulation of Wnt signaling pathway IEA
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005829 cytosol IEA
 molecular_functionGO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding IEA
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IEA
 molecular_functionGO:0042826 histone deacetylase binding IEA
 molecular_functionGO:0043565 sequence-specific DNA binding IEA


Pathways (from Reactome)
Pathway description
SUMOylation of transcription factors


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr