ENSGALG00000042201


Gallus gallus

Features
Gene ID: ENSGALG00000042201
  
Biological name :TP53BP1
  
Synonyms : TP53BP1 / tumor protein p53 binding protein 1
  
Possible biological names infered from orthology : P70399 / Q12888 / TP53-binding protein 1 / Trp53bp1
  
Species: Gallus gallus
  
Chr. number: 10
Strand: 1
Band:
Gene start: 20283723
Gene end: 20314616
  
Corresponding Affymetrix probe sets: GgaAffx.5368.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000047256
NCBI entrez gene - 415589     See in Manteia.
RefSeq - XM_004943995
RefSeq - XM_413957
RefSeq - XM_015292141
RefSeq - XM_015292143
swissprot - A0A1D5P3K1
Ensembl - ENSGALG00000042201
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 tp53bp1ENSDARG00000079000Danio rerio
 Q12888ENSG00000067369Homo sapiens
 P70399ENSMUSG00000043909Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR001357  BRCT domain
 IPR014722  Ribosomal protein L2, domain 2
 IPR015125  Tumour suppressor p53-binding protein-1 Tudor domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006281 DNA repair IEA
 biological_processGO:0006303 double-strand break repair via nonhomologous end joining IEA
 biological_processGO:0006974 cellular response to DNA damage stimulus IEA
 biological_processGO:0045830 positive regulation of isotype switching IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IEA
 biological_processGO:0051260 protein homooligomerization IEA
 biological_processGO:2000042 negative regulation of double-strand break repair via homologous recombination IEA
 cellular_componentGO:0000776 kinetochore IEA
 cellular_componentGO:0000781 chromosome, telomeric region IEA
 cellular_componentGO:0000784 nuclear chromosome, telomeric region IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005657 replication fork IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0016604 nuclear body IEA
 cellular_componentGO:0035861 site of double-strand break IEA
 cellular_componentGO:1990391 DNA repair complex IEA
 molecular_functionGO:0001102 RNA polymerase II activating transcription factor binding IEA
 molecular_functionGO:0002039 p53 binding IEA
 molecular_functionGO:0003684 damaged DNA binding IEA
 molecular_functionGO:0035064 methylated histone binding IEA
 molecular_functionGO:0042162 telomeric DNA binding IEA
 molecular_functionGO:0043565 sequence-specific DNA binding IEA
 molecular_functionGO:0061649 ubiquitin modification-dependent histone binding IEA


Pathways (from Reactome)
Pathway description
SUMOylation of transcription factors
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks
Nonhomologous End-Joining (NHEJ)
Processing of DNA double-strand break ends
G2/M DNA damage checkpoint


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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