ENSGALG00000042949


Gallus gallus

Features
Gene ID: ENSGALG00000042949
  
Biological name :MGMT
  
Synonyms : MGMT / O-6-methylguanine-DNA methyltransferase
  
Possible biological names infered from orthology : Methylated-DNA--protein-cysteine methyltransferase / P16455 / P26187
  
Species: Gallus gallus
  
Chr. number: 6
Strand: 1
Band:
Gene start: 34029566
Gene end: 34171713
  
Corresponding Affymetrix probe sets: Gga.12716.1.S1_at (Chicken Array)   Gga.6353.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000056888
Ensembl peptide - ENSGALP00000064073
Ensembl peptide - ENSGALP00000061676
Ensembl peptide - ENSGALP00000057994
Ensembl peptide - ENSGALP00000056107
NCBI entrez gene - 423965     See in Manteia.
RefSeq - XM_015289036
swissprot - A0A1L1RYX7
swissprot - A0A1D5PYE3
swissprot - A0A1D5PVC3
Ensembl - ENSGALG00000042949
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 mgmtENSDARG00000043275Danio rerio
 MGMTENSG00000170430Homo sapiens
 MgmtENSMUSG00000054612Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR001497  Methylated-DNA-[protein]-cysteine S-methyltransferase, active site
 IPR008332  Methylguanine DNA methyltransferase, ribonuclease-like domain
 IPR011991  ArsR-like helix-turn-helix domain
 IPR014048  Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006281 DNA repair IEA
 biological_processGO:0006307 DNA dealkylation involved in DNA repair IEA
 biological_processGO:0006974 cellular response to DNA damage stimulus IEA
 biological_processGO:0032259 methylation IEA
 biological_processGO:0043066 negative regulation of apoptotic process IEA
 biological_processGO:0043281 regulation of cysteine-type endopeptidase activity involved in apoptotic process IEA
 biological_processGO:2000781 positive regulation of double-strand break repair IEA
 cellular_componentGO:0005654 nucleoplasm IEA
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0003908 methylated-DNA-[protein]-cysteine S-methyltransferase activity IEA
 molecular_functionGO:0008168 methyltransferase activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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