ENSGALG00000043287


Gallus gallus

Features
Gene ID: ENSGALG00000043287
  
Biological name :CAV1
  
Synonyms : CAV1 / caveolin-1
  
Possible biological names infered from orthology : P49817 / Q03135
  
Species: Gallus gallus
  
Chr. number: 1
Strand: -1
Band:
Gene start: 25060566
Gene end: 25074918
  
Corresponding Affymetrix probe sets: Gga.5091.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000043610
NCBI entrez gene - 373996     See in Manteia.
RefSeq - NM_001105664
RefSeq Peptide - NP_001099134
swissprot - A0M8T8
Ensembl - ENSGALG00000043287
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 cav1ENSDARG00000103747Danio rerio
 CAV1ENSG00000105974Homo sapiens
 Cav1ENSMUSG00000007655Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
CAV3 / caveolin 3 / P51637* / P56539*ENSGALG0000000835158
CAV2 / caveolin-2 / P51636* / Q9WVC3*ENSGALG0000003329531


Protein motifs (from Interpro)
Interpro ID Name
 IPR001612  Caveolin
 IPR018361  Caveolin, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IEA
 biological_processGO:0000188 inactivation of MAPK activity IEA
 biological_processGO:0001525 angiogenesis IEA
 biological_processGO:0001570 vasculogenesis IEA
 biological_processGO:0001666 response to hypoxia IEA
 biological_processGO:0001937 negative regulation of endothelial cell proliferation IEA
 biological_processGO:0001960 negative regulation of cytokine-mediated signaling pathway IEA
 biological_processGO:0002026 regulation of the force of heart contraction IEA
 biological_processGO:0002931 response to ischemia IEA
 biological_processGO:0003057 regulation of the force of heart contraction by chemical signal IEA
 biological_processGO:0006641 triglyceride metabolic process IEA
 biological_processGO:0006816 calcium ion transport IEA
 biological_processGO:0006874 cellular calcium ion homeostasis IEA
 biological_processGO:0006940 regulation of smooth muscle contraction IEA
 biological_processGO:0007519 skeletal muscle tissue development IEA
 biological_processGO:0007595 lactation IEA
 biological_processGO:0008104 protein localization IEA
 biological_processGO:0008285 negative regulation of cell proliferation IEA
 biological_processGO:0009617 response to bacterium IEA
 biological_processGO:0009968 negative regulation of signal transduction IEA
 biological_processGO:0010524 positive regulation of calcium ion transport into cytosol IEA
 biological_processGO:0010608 posttranscriptional regulation of gene expression IEA
 biological_processGO:0010628 positive regulation of gene expression IEA
 biological_processGO:0010952 positive regulation of peptidase activity IEA
 biological_processGO:0019065 receptor-mediated endocytosis of virus by host cell IEA
 biological_processGO:0019217 regulation of fatty acid metabolic process IEA
 biological_processGO:0019915 lipid storage IEA
 biological_processGO:0030193 regulation of blood coagulation IEA
 biological_processGO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway IEA
 biological_processGO:0030857 negative regulation of epithelial cell differentiation IEA
 biological_processGO:0030879 mammary gland development IEA
 biological_processGO:0031295 T cell costimulation IEA
 biological_processGO:0031397 negative regulation of protein ubiquitination IEA
 biological_processGO:0031398 positive regulation of protein ubiquitination IEA
 biological_processGO:0031623 receptor internalization IEA
 biological_processGO:0032091 negative regulation of protein binding IEA
 biological_processGO:0032092 positive regulation of protein binding IEA
 biological_processGO:0032570 response to progesterone IEA
 biological_processGO:0033137 negative regulation of peptidyl-serine phosphorylation IEA
 biological_processGO:0033138 positive regulation of peptidyl-serine phosphorylation IEA
 biological_processGO:0033484 nitric oxide homeostasis IEA
 biological_processGO:0034141 positive regulation of toll-like receptor 3 signaling pathway IEA
 biological_processGO:0042310 vasoconstriction IEA
 biological_processGO:0042532 negative regulation of tyrosine phosphorylation of STAT protein IEA
 biological_processGO:0042632 cholesterol homeostasis IEA
 biological_processGO:0043085 positive regulation of catalytic activity IEA
 biological_processGO:0043407 negative regulation of MAP kinase activity IEA
 biological_processGO:0043409 negative regulation of MAPK cascade IEA
 biological_processGO:0043627 response to estrogen IEA
 biological_processGO:0045019 negative regulation of nitric oxide biosynthetic process IEA
 biological_processGO:0045907 positive regulation of vasoconstriction IEA
 biological_processGO:0046426 negative regulation of JAK-STAT cascade IEA
 biological_processGO:0048550 negative regulation of pinocytosis IEA
 biological_processGO:0051001 negative regulation of nitric-oxide synthase activity IEA
 biological_processGO:0051259 protein complex oligomerization IEA
 biological_processGO:0051260 protein homooligomerization IEA
 biological_processGO:0051480 regulation of cytosolic calcium ion concentration IEA
 biological_processGO:0051592 response to calcium ion IEA
 biological_processGO:0051899 membrane depolarization IEA
 biological_processGO:0052547 regulation of peptidase activity IEA
 biological_processGO:0055074 calcium ion homeostasis IEA
 biological_processGO:0060056 mammary gland involution IEA
 biological_processGO:0060355 positive regulation of cell adhesion molecule production IEA
 biological_processGO:0060546 negative regulation of necroptotic process IEA
 biological_processGO:0061099 negative regulation of protein tyrosine kinase activity IEA
 biological_processGO:0070836 caveola assembly IEA
 biological_processGO:0071360 cellular response to exogenous dsRNA IEA
 biological_processGO:0071375 cellular response to peptide hormone stimulus IEA
 biological_processGO:0071455 cellular response to hyperoxia IEA
 biological_processGO:0071560 cellular response to transforming growth factor beta stimulus IEA
 biological_processGO:0072584 caveolin-mediated endocytosis IEA
 biological_processGO:0086091 regulation of heart rate by cardiac conduction IEA
 biological_processGO:0086098 angiotensin-activated signaling pathway involved in heart process IEA
 biological_processGO:0090090 negative regulation of canonical Wnt signaling pathway IEA
 biological_processGO:0090263 positive regulation of canonical Wnt signaling pathway IEA
 biological_processGO:0097190 apoptotic signaling pathway IEA
 biological_processGO:0098903 regulation of membrane repolarization during action potential IEA
 biological_processGO:0098911 regulation of ventricular cardiac muscle cell action potential IEA
 biological_processGO:1900027 regulation of ruffle assembly IEA
 biological_processGO:1900085 negative regulation of peptidyl-tyrosine autophosphorylation IEA
 biological_processGO:1901380 negative regulation of potassium ion transmembrane transport IEA
 biological_processGO:1901844 regulation of cell communication by electrical coupling involved in cardiac conduction IEA
 biological_processGO:1903598 positive regulation of gap junction assembly IEA
 biological_processGO:1903609 negative regulation of inward rectifier potassium channel activity IEA
 biological_processGO:2000286 receptor internalization involved in canonical Wnt signaling pathway IEA
 biological_processGO:2000535 regulation of entry of bacterium into host cell IEA
 biological_processGO:2000811 negative regulation of anoikis IEA
 biological_processGO:2001238 positive regulation of extrinsic apoptotic signaling pathway IEA
 biological_processGO:2001244 positive regulation of intrinsic apoptotic signaling pathway IEA
 cellular_componentGO:0000139 Golgi membrane IEA
 cellular_componentGO:0002080 acrosomal membrane IEA
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005768 endosome IEA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0005887 integral component of plasma membrane IEA
 cellular_componentGO:0005901 caveola IEA
 cellular_componentGO:0005925 focal adhesion IEA
 cellular_componentGO:0005929 cilium IEA
 cellular_componentGO:0005938 cell cortex IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0031410 cytoplasmic vesicle IEA
 cellular_componentGO:0032991 protein-containing complex IEA
 cellular_componentGO:0034098 VCP-NPL4-UFD1 AAA ATPase complex IEA
 cellular_componentGO:0045121 membrane raft IEA
 cellular_componentGO:0048471 perinuclear region of cytoplasm IEA
 molecular_functionGO:0005102 signaling receptor binding IEA
 molecular_functionGO:0005198 structural molecule activity IEA
 molecular_functionGO:0016504 peptidase activator activity IEA
 molecular_functionGO:0019899 enzyme binding IEA
 molecular_functionGO:0019901 protein kinase binding IEA
 molecular_functionGO:0030674 protein binding, bridging IEA
 molecular_functionGO:0032947 protein-containing complex scaffold activity IEA
 molecular_functionGO:0042802 identical protein binding IEA
 molecular_functionGO:0044325 ion channel binding IEA
 molecular_functionGO:0046982 protein heterodimerization activity IEA
 molecular_functionGO:0048365 Rac GTPase binding IEA
 molecular_functionGO:0050998 nitric-oxide synthase binding IEA
 molecular_functionGO:0051117 ATPase binding IEA
 molecular_functionGO:0070320 inward rectifier potassium channel inhibitor activity IEA


Pathways (from Reactome)
Pathway description
Basigin interactions
Disassembly of the destruction complex and recruitment of AXIN to the membrane


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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