ENSMUSG00000000439


Mus musculus

Features
Gene ID: ENSMUSG00000000439
  
Biological name :Mkrn2
  
Synonyms : Mkrn2 / Probable E3 ubiquitin-protein ligase makorin-2 / Q9ERV1
  
Possible biological names infered from orthology : makorin ring finger protein 2 / Q9H000
  
Species: Mus musculus
  
Chr. number: 6
Strand: 1
Band: E3
Gene start: 115601902
Gene end: 115622624
  
Corresponding Affymetrix probe sets: 10540923 (MoGene1.0st)   1417935_at (Mouse Genome 430 2.0 Array)   1420090_at (Mouse Genome 430 2.0 Array)   1448897_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000000449
NCBI entrez gene - 67027     See in Manteia.
MGI - MGI:1914277
RefSeq - NM_023290
RefSeq - XM_011241431
RefSeq Peptide - NP_075779
swissprot - Q9ERV1
Ensembl - ENSMUSG00000000439
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 mkrn2ENSDARG00000007630Danio rerio
 MKRN2ENSGALG00000004991Gallus gallus
 MKRN2ENSG00000075975Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Mkrn1 / Q9QXP6 / makorin, ring finger protein, 1 / Q9UHC7*ENSMUSG0000002992244
Mkrn3 / Q60764 / Probable E3 ubiquitin-protein ligase makorin-3 / Q13064* / makorin ring finger protein 3*ENSMUSG0000007052734


Protein motifs (from Interpro)
Interpro ID Name
 IPR000571  Zinc finger, CCCH-type
 IPR001841  Zinc finger, RING-type
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR017907  Zinc finger, RING-type, conserved site
 IPR018957  Zinc finger, C3HC4 RING-type
 IPR026293  Probable E3 ubiquitin-protein ligase makorin-2
 IPR036855  Zinc finger, CCCH-type superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0008150 biological_process ND
 biological_processGO:0016567 protein ubiquitination IEA
 cellular_componentGO:0005622 intracellular IEA
 molecular_functionGO:0003674 molecular_function ND
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0008210 increased mature B cell number "greater number of the mature form of B cells, a type of lymphocyte whose defining characteristic is the expression of an immunoglobulin complex" [CL:0000785, ISBN:0781735149]
Show

Allelic Composition: Mc1rtm1.1(KOMP)Vlcg/Mc1rtm1.1(KOMP)Vlcg
Genetic Background: C57BL/6N-Mc1rtm1.1(KOMP)Vlcg/Ucd

 MP:0008346 increased gamma-delta T cell number "greater number of immature or mature T cells expressing an gamma-delta T cell receptor complex" [CL:0000798, ISBN:0781735149]
Show

Allelic Composition: Mc1rtm1.1(KOMP)Vlcg/Mc1rtm1.1(KOMP)Vlcg
Genetic Background: C57BL/6N-Mc1rtm1.1(KOMP)Vlcg/Ucd

 MP:0010844 increased effector memory CD4-positive, alpha-beta T cell number "increased number of CD4-positive, alpha-beta memory T cells with the phenotype CCR7-negative, CD127-positive, CD45RO-positive, and CD25-negative" [CL:0000905, GO_REF:0000031, GOC:add, GOC:pam, GOC:tfm]
Show

Allelic Composition: Mc1rtm1.1(KOMP)Vlcg/Mc1rtm1.1(KOMP)Vlcg
Genetic Background: C57BL/6N-Mc1rtm1.1(KOMP)Vlcg/Ucd

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

1 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr