ENSMUSG00000001056


Mus musculus

Features
Gene ID: ENSMUSG00000001056
  
Biological name :Nhp2
  
Synonyms : H/ACA ribonucleoprotein complex subunit 2 / Nhp2 / Q9CRB2
  
Possible biological names infered from orthology : NHP2 ribonucleoprotein / Q9NX24
  
Species: Mus musculus
  
Chr. number: 11
Strand: 1
Band: B1.3
Gene start: 51619735
Gene end: 51623714
  
Corresponding Affymetrix probe sets: 10375880 (MoGene1.0st)   1416605_at (Mouse Genome 430 2.0 Array)   1416606_s_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000120014
NCBI entrez gene - 52530     See in Manteia.
MGI - MGI:1098547
RefSeq - NM_026631
RefSeq Peptide - NP_080907
swissprot - Q9CRB2
Ensembl - ENSMUSG00000001056
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 nhp2ENSDARG00000069422Danio rerio
 NHP2ENSGALG00000033666Gallus gallus
 NHP2ENSG00000145912Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR002415  H/ACA ribonucleoprotein complex, subunit Nhp2, eukaryote
 IPR004038  Ribosomal protein L7Ae/L30e/S12e/Gadd45
 IPR018492  Ribosomal protein L7Ae/L8/Nhp2 family
 IPR029064  50S ribosomal protein L30e-like


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000469 cleavage involved in rRNA processing IBA
 biological_processGO:0000470 maturation of LSU-rRNA IBA
 biological_processGO:0006364 rRNA processing IEA
 biological_processGO:0006412 translation IBA
 biological_processGO:0031118 rRNA pseudouridine synthesis ISS
 biological_processGO:0031120 snRNA pseudouridine synthesis IBA
 biological_processGO:0042254 ribosome biogenesis IEA
 biological_processGO:1904874 positive regulation of telomerase RNA localization to Cajal body IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005697 telomerase holoenzyme complex IEA
 cellular_componentGO:0005730 nucleolus IEA
 cellular_componentGO:0005732 small nucleolar ribonucleoprotein complex ISS
 cellular_componentGO:0015030 Cajal body IEA
 cellular_componentGO:0031429 box H/ACA snoRNP complex IEA
 cellular_componentGO:0090661 box H/ACA telomerase RNP complex IEA
 molecular_functionGO:0003723 RNA binding ISO
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0030515 snoRNA binding ISS
 molecular_functionGO:0034513 box H/ACA snoRNA binding IEA
 molecular_functionGO:0070034 telomerase RNA binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000150 abnormal rib morphology "malformed bones forming the bony wall of the chest" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:50311]
Show

Allelic Composition: Ltatm1.1(KOMP)Vlcg/Ltatm1.1(KOMP)Vlcg
Genetic Background: C57BL/6N-Ltatm1.1(KOMP)Vlcg/Ucd

 MP:0000322 increased granulocyte number "greater than expected number of leukocytes that have abundant granules in the cytoplasm: basophils, neutrophils, or eosinophils" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Ltatm1.1(KOMP)Vlcg/Ltatm1.1(KOMP)Vlcg
Genetic Background: C57BL/6N-Ltatm1.1(KOMP)Vlcg/Ucd

 MP:0002599 increased mean platelet volume "increased content of platelet cells over the norm" [cml:Cathleen M. Lutz, Mouse Genome Informatics Curator]
Show

Allelic Composition: Ltatm1.1(KOMP)Vlcg/Ltatm1.1(KOMP)Vlcg
Genetic Background: C57BL/6N-Ltatm1.1(KOMP)Vlcg/Ucd

 MP:0011100 complete preweaning lethality "death of all organisms of a given genotype in a population between fertilization and weaning age (Mus: approximately 3-4 weeks of age)" [MGI:csmith]
Show

Allelic Composition: Nampttm1.1(KOMP)Vlcg/Nampttm1.1(KOMP)Vlcg
Genetic Background: C57BL/6N-Nampttm1.1(KOMP)Vlcg/Ucd

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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