ENSMUSG00000001380


Mus musculus

Features
Gene ID: ENSMUSG00000001380
  
Biological name :Hars
  
Synonyms : Hars / Histidine--tRNA ligase, cytoplasmic / Q61035
  
Possible biological names infered from orthology : histidyl-tRNA synthetase / P12081
  
Species: Mus musculus
  
Chr. number: 18
Strand: -1
Band: B2
Gene start: 36766530
Gene end: 36783205
  
Corresponding Affymetrix probe sets: 10458398 (MoGene1.0st)   1417024_at (Mouse Genome 430 2.0 Array)   1438510_a_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000001416
NCBI entrez gene - 15115     See in Manteia.
MGI - MGI:108087
RefSeq - NM_008214
RefSeq Peptide - NP_032240
swissprot - Q61035
Ensembl - ENSMUSG00000001380
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 harsENSDARG00000003693Danio rerio
 ENSGALG00000029346Gallus gallus
 HARSENSGALG00000035080Gallus gallus
 HARSENSG00000170445Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Hars2 / Q99KK9 / Probable histidine--tRNA ligase, mitochondrial / P49590* / histidyl-tRNA synthetase 2, mitochondrial*ENSMUSG0000001914367


Protein motifs (from Interpro)
Interpro ID Name
 IPR000738  WHEP-TRS domain
 IPR004154  Anticodon-binding
 IPR004516  Histidine-tRNA ligase/ATP phosphoribosyltransferase regulatory subunit
 IPR006195  Aminoacyl-tRNA synthetase, class II
 IPR009068  S15/NS1, RNA-binding
 IPR015807  Histidine-tRNA ligase
 IPR033656  Histidyl-anticodon-binding
 IPR036621  Anticodon-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006412 translation IEA
 biological_processGO:0006418 tRNA aminoacylation for protein translation IEA
 biological_processGO:0006427 histidyl-tRNA aminoacylation IEA
 biological_processGO:0032543 mitochondrial translation IBA
 cellular_componentGO:0005737 cytoplasm ISO
 cellular_componentGO:0005739 mitochondrion IBA
 cellular_componentGO:0005829 cytosol IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004812 aminoacyl-tRNA ligase activity IEA
 molecular_functionGO:0004821 histidine-tRNA ligase activity IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016874 ligase activity IEA
 molecular_functionGO:0042802 identical protein binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001967 deafness "inability to hear" [J:57651]
Show

Allelic Composition: Grxcr1mpc265H/Grxcr1mpc265H
Genetic Background: involves: BALB/c * C3H/HeH * C57BL/6J

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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