ENSMUSG00000002980


Mus musculus

Features
Gene ID: ENSMUSG00000002980
  
Biological name :Bcam
  
Synonyms : Basal cell adhesion molecule / Bcam / Q9R069
  
Possible biological names infered from orthology : basal cell adhesion molecule (Lutheran blood group) / P50895
  
Species: Mus musculus
  
Chr. number: 7
Strand: -1
Band: A3
Gene start: 19756131
Gene end: 19771016
  
Corresponding Affymetrix probe sets: 10560655 (MoGene1.0st)   1424791_a_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000003061
Ensembl peptide - ENSMUSP00000121145
Ensembl peptide - ENSMUSP00000117998
NCBI entrez gene - 57278     See in Manteia.
MGI - MGI:1929940
RefSeq - NM_020486
RefSeq Peptide - NP_065232
swissprot - D6RE44
swissprot - D3YTK7
swissprot - Q9R069
Ensembl - ENSMUSG00000002980
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 bcamENSDARG00000090190Danio rerio
 BCAMENSG00000187244Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Mcam / Q8R2Y2 / Cell surface glycoprotein MUC18 / P43121* / melanoma cell adhesion molecule*ENSMUSG0000003213527
Alcam / Q61490 / CD166 antigen / Q13740* / activated leukocyte cell adhesion molecule*ENSMUSG0000002263620


Protein motifs (from Interpro)
Interpro ID Name
 IPR003598  Immunoglobulin subtype 2
 IPR003599  Immunoglobulin subtype
 IPR007110  Immunoglobulin-like domain
 IPR013098  Immunoglobulin I-set
 IPR013162  CD80-like, immunoglobulin C2-set
 IPR013783  Immunoglobulin-like fold
 IPR036179  Immunoglobulin-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007155 cell adhesion IDA
 biological_processGO:0007160 cell-matrix adhesion IEA
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005886 plasma membrane IDA
 cellular_componentGO:0005887 integral component of plasma membrane ISS
 cellular_componentGO:0009986 cell surface IDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0031012 extracellular matrix IEA
 molecular_functionGO:0005055 laminin receptor activity IEA
 molecular_functionGO:0008022 protein C-terminus binding IEA
 molecular_functionGO:0043236 laminin binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000495 abnormal colon morphology "malformation of the portion of the large intestine between the cecum and the rectum" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: PhbGt(BGB069)Byg/Phb+
Genetic Background: involves: 129P2/OlaHsd * C57BL

 MP:0001260 increased body weight "greater than normal average weight " [J:33400]
Show

Allelic Composition: PhbGt(BGB069)Byg/Phb+
Genetic Background: involves: 129P2/OlaHsd * C57BL

 MP:0002169 no phenotype detected "normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Casp9tm1Flv/Casp9tm1Flv
Genetic Background: B6.129S1-Casp9tm1Flv

 MP:0004002 abnormal jejunum morphology "malformation of the portion of the small intestine that extends from the duodenum to the ileum" [monikat:Monika Tomczuk, Mouse Genome Informatics Curator]
Show

Allelic Composition: PhbGt(BGB069)Byg/Phb+
Genetic Background: involves: 129P2/OlaHsd * C57BL

 MP:0005325 abnormal glomerulus "anomalous structure of the capillary loops of the kidney that normally function as a filtration unit" [J:57971, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: PhbGt(BGB069)Byg/Phb+
Genetic Background: involves: 129P2/OlaHsd * C57BL

 MP:0006087 increased body mass index "greater than normal average of a measure of weight for height" [ncbi:NCBI request, smb:Susan M Bello, Mouse Genome Informatics Curator]
Show

Allelic Composition: PhbGt(BGB069)Byg/Phb+
Genetic Background: involves: 129P2/OlaHsd * C57BL

 MP:0011320 abnormal glomerular capillary morphology "any structural anomaly of the small branching blood vessels in the kidney glomerulus that receives blood from the kidney afferent arterioles; these capillaries are under high pressure for filtering within the glomerulus" [MGI:csmith]
Show

Allelic Composition: PhbGt(BGB069)Byg/Phb+
Genetic Background: involves: 129P2/OlaHsd * C57BL

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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