ENSMUSG00000022636


Mus musculus

Features
Gene ID: ENSMUSG00000022636
  
Biological name :Alcam
  
Synonyms : Alcam / CD166 antigen / Q61490
  
Possible biological names infered from orthology : activated leukocyte cell adhesion molecule / Q13740
  
Species: Mus musculus
  
Chr. number: 16
Strand: -1
Band: B5
Gene start: 52248996
Gene end: 52454074
  
Corresponding Affymetrix probe sets: 10439895 (MoGene1.0st)   1426300_at (Mouse Genome 430 2.0 Array)   1426301_at (Mouse Genome 430 2.0 Array)   1437466_at (Mouse Genome 430 2.0 Array)   1437467_at (Mouse Genome 430 2.0 Array)   1443086_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000023312
Ensembl peptide - ENSMUSP00000129714
Ensembl peptide - ENSMUSP00000130563
Ensembl peptide - ENSMUSP00000131001
Ensembl peptide - ENSMUSP00000127141
NCBI entrez gene - 11658     See in Manteia.
MGI - MGI:1313266
RefSeq - XM_006521714
RefSeq - NM_009655
RefSeq Peptide - NP_001318039
RefSeq Peptide - NP_033785
swissprot - Q54AJ5
swissprot - Q5MPX5
swissprot - Q61490
swissprot - E9Q4G8
swissprot - F6QH25
swissprot - E9Q3Q6
Ensembl - ENSMUSG00000022636
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 alcamaENSDARG00000026531Danio rerio
 alcambENSDARG00000058538Danio rerio
 ALCAMENSGALG00000015348Gallus gallus
 ALCAMENSG00000170017Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Mcam / Q8R2Y2 / Cell surface glycoprotein MUC18 / P43121* / melanoma cell adhesion molecule*ENSMUSG0000003213521
Bcam / Q9R069 / Basal cell adhesion molecule / P50895* / basal cell adhesion molecule (Lutheran blood group)*ENSMUSG0000000298021


Protein motifs (from Interpro)
Interpro ID Name
 IPR003599  Immunoglobulin subtype
 IPR007110  Immunoglobulin-like domain
 IPR013162  CD80-like, immunoglobulin C2-set
 IPR013783  Immunoglobulin-like fold
 IPR021157  Cytochrome c1, transmembrane anchor, C-terminal
 IPR036179  Immunoglobulin-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002250 adaptive immune response IEA
 biological_processGO:0002376 immune system process IEA
 biological_processGO:0007155 cell adhesion ISS
 biological_processGO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules IEA
 biological_processGO:0007411 axon guidance IMP
 biological_processGO:0008045 motor neuron axon guidance IMP
 biological_processGO:0031290 retinal ganglion cell axon guidance ISS
 biological_processGO:0048846 axon extension involved in axon guidance ISS
 biological_processGO:1990138 neuron projection extension ISS
 cellular_componentGO:0001772 immunological synapse IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0005887 integral component of plasma membrane ISS
 cellular_componentGO:0009897 external side of plasma membrane IDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030424 axon IDA
 cellular_componentGO:0030425 dendrite IEA
 cellular_componentGO:0031226 intrinsic component of plasma membrane IEA
 cellular_componentGO:0042101 T cell receptor complex IEA
 cellular_componentGO:0042995 cell projection IEA
 cellular_componentGO:0043025 neuronal cell body IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0042802 identical protein binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000940 abnormal motor neuron innervation "misprojection or failure to bundle motor axons to an effector tissue" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:CLS, J:60159]
Show

Allelic Composition: Pax3Sp-7H/Pax3Sp-7H
Genetic Background: involves: C3H/HeH * C57BL/6

 MP:0001325 abnormal retina morphology "structural or developmental anomaly of the thin layer of neural tissue lining the back of the eyeball which contains visual receptors " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Pax3Sp-7H/Pax3Sp-7H
Genetic Background: involves: C3H/HeH * C57BL/6

 MP:0003729 abnormal photoreceptor outer segments "malformation/anomalous structure of the photoreceptor layer which contains stacks of membranous discs that are rich in the visual pigment rhodopsin " [monikat:Monika Tomczuk, Mouse Genome Informatics Curator]
Show

Allelic Composition: Pax3Sp-7H/Pax3Sp-7H
Genetic Background: involves: C3H/HeH * C57BL/6

 MP:0005241 abnormal retinal ganglion layer morphology "anomalous structure of the innermost nuclear layer of the retina, which projects axons through the optic nerve to the brain " [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
Show

Allelic Composition: Pax3Sp-7H/Pax3Sp-7H
Genetic Background: involves: C3H/HeH * C57BL/6

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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