ENSG00000170017


Homo sapiens

Features
Gene ID: ENSG00000170017
  
Biological name :ALCAM
  
Synonyms : activated leukocyte cell adhesion molecule / ALCAM / Q13740
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 3
Strand: 1
Band: q13.11
Gene start: 105366909
Gene end: 105576900
  
Corresponding Affymetrix probe sets: 1569362_at (Human Genome U133 Plus 2.0 Array)   201951_at (Human Genome U133 Plus 2.0 Array)   201952_at (Human Genome U133 Plus 2.0 Array)   240655_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000305988
Ensembl peptide - ENSP00000418213
Ensembl peptide - ENSP00000418937
Ensembl peptide - ENSP00000419236
NCBI entrez gene - 214     See in Manteia.
OMIM - 601662
RefSeq - NM_001243280
RefSeq - NM_001627
RefSeq - NM_001243281
RefSeq Peptide - NP_001230209
RefSeq Peptide - NP_001618
RefSeq Peptide - NP_001230210
swissprot - Q13740
swissprot - F5GXJ9
swissprot - H7C543
Ensembl - ENSG00000170017
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 alcamaENSDARG00000026531Danio rerio
 alcambENSDARG00000058538Danio rerio
 ALCAMENSGALG00000015348Gallus gallus
 AlcamENSMUSG00000022636Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
MCAM / P43121 / melanoma cell adhesion moleculeENSG0000007670622
BCAM / P50895 / basal cell adhesion molecule (Lutheran blood group)ENSG0000018724422


Protein motifs (from Interpro)
Interpro ID Name
 IPR003598  Immunoglobulin subtype 2
 IPR003599  Immunoglobulin subtype
 IPR007110  Immunoglobulin-like domain
 IPR013106  Immunoglobulin V-set domain
 IPR013162  CD80-like, immunoglobulin C2-set
 IPR013783  Immunoglobulin-like fold
 IPR021157  Cytochrome c1, transmembrane anchor, C-terminal
 IPR036179  Immunoglobulin-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002250 adaptive immune response IEA
 biological_processGO:0002376 immune system process IEA
 biological_processGO:0007155 cell adhesion TAS
 biological_processGO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules IMP
 biological_processGO:0007165 signal transduction TAS
 biological_processGO:0007411 axon guidance IEA
 biological_processGO:0008045 motor neuron axon guidance IEA
 biological_processGO:0031290 retinal ganglion cell axon guidance ISS
 biological_processGO:0048846 axon extension involved in axon guidance ISS
 biological_processGO:1990138 neuron projection extension ISS
 cellular_componentGO:0001772 immunological synapse IDA
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0005887 integral component of plasma membrane ISS
 cellular_componentGO:0005925 focal adhesion HDA
 cellular_componentGO:0009897 external side of plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030424 axon ISS
 cellular_componentGO:0030425 dendrite IEA
 cellular_componentGO:0031226 intrinsic component of plasma membrane IDA
 cellular_componentGO:0042101 T cell receptor complex IDA
 cellular_componentGO:0042995 cell projection IEA
 cellular_componentGO:0043025 neuronal cell body IEA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0005102 signaling receptor binding TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0042802 identical protein binding IPI


Pathways (from Reactome)
Pathway description
L1CAM interactions


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000198910 L1CAM / P32004 / L1 cell adhesion molecule  / complex / reaction






 

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