ENSMUSG00000003282


Mus musculus

Features
Gene ID: ENSMUSG00000003282
  
Biological name :Plag1
  
Synonyms : Plag1 / Q9QYE0 / Zinc finger protein PLAG1
  
Possible biological names infered from orthology : PLAG1 zinc finger / Q6DJT9
  
Species: Mus musculus
  
Chr. number: 4
Strand: -1
Band: A1
Gene start: 3900996
Gene end: 3938423
  
Corresponding Affymetrix probe sets: 10511333 (MoGene1.0st)   1421745_at (Mouse Genome 430 2.0 Array)   1443943_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000003369
Ensembl peptide - ENSMUSP00000117532
Ensembl peptide - ENSMUSP00000119937
NCBI entrez gene - 56711     See in Manteia.
MGI - MGI:1891916
RefSeq - XM_017320331
RefSeq - NM_019969
RefSeq - XM_006538122
RefSeq - XM_011250079
RefSeq - XM_017320330
RefSeq - XM_006538116
RefSeq - XM_006538121
RefSeq Peptide - NP_064353
swissprot - Q9QYE0
swissprot - D6RES7
Ensembl - ENSMUSG00000003282
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 plag1ENSDARG00000051926Danio rerio
 PLAG1ENSGALG00000015407Gallus gallus
 PLAG1ENSG00000181690Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Plagl2 / PLAG1 like zinc finger 2 / Q9UPG8*ENSMUSG0000005141343
Plagl1 / Q9UM63* / PLAG1 like zinc finger 1*ENSMUSG0000001981738


Protein motifs (from Interpro)
Interpro ID Name
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR013087  Zinc finger C2H2-type
 IPR027765  Zinc finger protein PLAG1
 IPR036236  Zinc finger C2H2 superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006366 transcription by RNA polymerase II IEA
 biological_processGO:0006915 apoptotic process IBA
 biological_processGO:0010628 positive regulation of gene expression IDA
 biological_processGO:0010629 negative regulation of gene expression IDA
 biological_processGO:0022612 gland morphogenesis IMP
 biological_processGO:0035264 multicellular organism growth IMP
 biological_processGO:0035265 organ growth IMP
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IEA
 biological_processGO:0060252 positive regulation of glial cell proliferation IDA
 biological_processGO:0060736 prostate gland growth IMP
 cellular_componentGO:0005634 nucleus IBA
 cellular_componentGO:0016607 nuclear speck IEA
 molecular_functionGO:0000978 RNA polymerase II proximal promoter sequence-specific DNA binding IEA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding IBA
 molecular_functionGO:0001077 transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding IEA
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000661 small ventral prostate "reduced size of lateral lobe of the prostate" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:63764]
Show

Allelic Composition: Glra1spd/Glra1spd
Genetic Background: B6C3Fe a/a-Glra1spd/J

 MP:0001290 delayed eyelid opening "late average time for the first postnatal eye opening" [J:17792]
Show

Allelic Composition: Glra1spd/Glra1spd
Genetic Background: B6C3Fe a/a-Glra1spd/J

 MP:0001732 postnatal growth retardation "slow or limited development after birth " [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Glra1spd/Glra1spd
Genetic Background: B6C3Fe a/a-Glra1spd/J

 MP:0001922 reduced male fertility "reduced ability of male to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:61340]
Show

Allelic Composition: Glra1spd/Glra1spd
Genetic Background: B6C3Fe a/a-Glra1spd/J

 MP:0001935 reduced litter size "fewer live born pups in a litter compared to average" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Glra1spd/Glra1spd
Genetic Background: B6C3Fe a/a-Glra1spd/J

 MP:0002059 abnormal seminal gland morphology "anomalous structure of one of the two folded, sac shaped, glands that is a diverticulum of the ductus deferens " [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Glra1spd/Glra1spd
Genetic Background: B6C3Fe a/a-Glra1spd/J

 MP:0004910 decreased seminal gland weight "reduction in the weight of one or both of the two folded, sac shaped, glands that is a diverticulum of the ductus deferens" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Glra1spd/Glra1spd
Genetic Background: B6C3Fe a/a-Glra1spd/J

 MP:0009429 decreased embryo weight "reduced weight of an embryo compared to littermates or other controls (sensu Mus: up to E14, or the completion of organogenesis)" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Glra1spd/Glra1spd
Genetic Background: B6C3Fe a/a-Glra1spd/J

 MP:0013319 seminal vesicle atrophy "acquired size diminution of the seminal vesicles, associated with wasting as from death and reabsorbtion of cells, diminished cellular proliferation, decreased cellular volume, pressure, ischemia, malnutrition, reduced function or malfunction, or hormonal changes" [MGI:Anna]
Show

Allelic Composition: Glra1spd/Glra1spd
Genetic Background: B6C3Fe a/a-Glra1spd/J

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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