ENSMUSG00000003665


Mus musculus

Features
Gene ID: ENSMUSG00000003665
  
Biological name :Has1
  
Synonyms : Has1 / Hyaluronan synthase 1 / Q61647
  
Possible biological names infered from orthology : Q92839
  
Species: Mus musculus
  
Chr. number: 17
Strand: -1
Band: A3.2
Gene start: 17843328
Gene end: 17855188
  
Corresponding Affymetrix probe sets: 10448117 (MoGene1.0st)   1420590_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000003762
NCBI entrez gene - 15116     See in Manteia.
MGI - MGI:106590
RefSeq - NM_008215
RefSeq - XM_011246309
RefSeq Peptide - NP_032241
swissprot - Q61647
Ensembl - ENSMUSG00000003665
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 has1ENSDARG00000042983Danio rerio
 HAS1ENSG00000105509Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Has3 / O08650 / Mus musculus hyaluronan synthase 3 (Has3), transcript variant 2, mRNA. / O00219* / hyaluronan synthase 3*ENSMUSG0000003191053
Has2 / P70312 / Hyaluronan synthase 2 / Q92819*ENSMUSG0000002236750


Protein motifs (from Interpro)
Interpro ID Name
 IPR028385  Hyaluronan synthase 1
 IPR029044  Nucleotide-diphospho-sugar transferases


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007155 cell adhesion IBA
 biological_processGO:0010764 negative regulation of fibroblast migration IEA
 biological_processGO:0030213 hyaluronan biosynthetic process IDA
 biological_processGO:0036120 cellular response to platelet-derived growth factor stimulus IEA
 biological_processGO:0044849 estrous cycle IEA
 biological_processGO:0045226 extracellular polysaccharide biosynthetic process IDA
 biological_processGO:0085029 extracellular matrix assembly IDA
 cellular_componentGO:0005737 cytoplasm IDA
 cellular_componentGO:0005887 integral component of plasma membrane IBA
 cellular_componentGO:0016020 membrane IDA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0016757 transferase activity, transferring glycosyl groups IEA
 molecular_functionGO:0050501 hyaluronan synthase activity IDA


Pathways (from Reactome)
Pathway description
Hyaluronan biosynthesis and export


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0002169 no phenotype detected "normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Runx1tm2.1(Runx1/Mecom)Homy/Runx1+
Genetic Background: B6.129P2-Runx1tm2.1(Runx1/Mecom)Homy

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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