ENSMUSG00000031910


Mus musculus

Features
Gene ID: ENSMUSG00000031910
  
Biological name :Has3
  
Synonyms : Has3 / Mus musculus hyaluronan synthase 3 (Has3), transcript variant 2, mRNA. / O08650
  
Possible biological names infered from orthology : hyaluronan synthase 3 / O00219
  
Species: Mus musculus
  
Chr. number: 8
Strand: 1
Band: D3
Gene start: 106870242
Gene end: 106884566
  
Corresponding Affymetrix probe sets: 10575095 (MoGene1.0st)   1420589_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000034385
Ensembl peptide - ENSMUSP00000135303
Ensembl peptide - ENSMUSP00000135596
NCBI entrez gene - 15118     See in Manteia.
MGI - MGI:109599
RefSeq - XM_006530701
RefSeq - NM_001331048
RefSeq - NM_008217
RefSeq - XM_006530699
RefSeq - XM_006530700
RefSeq Peptide - NP_001317977
RefSeq Peptide - NP_032243
swissprot - O08650
swissprot - H3BL01
Ensembl - ENSMUSG00000031910
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 has3ENSDARG00000057210Danio rerio
 HAS3ENSGALG00000000630Gallus gallus
 HAS3ENSG00000103044Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Has2 / P70312 / Hyaluronan synthase 2 / Q92819*ENSMUSG0000002236769
Has1 / Q61647 / Hyaluronan synthase 1 / Q92839*ENSMUSG0000000366555


Protein motifs (from Interpro)
Interpro ID Name
 IPR026108  Hyaluronan synthase 3
 IPR029044  Nucleotide-diphospho-sugar transferases


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007155 cell adhesion IBA
 biological_processGO:0030213 hyaluronan biosynthetic process IEA
 biological_processGO:0045226 extracellular polysaccharide biosynthetic process IDA
 biological_processGO:0045893 positive regulation of transcription, DNA-templated ISO
 biological_processGO:0085029 extracellular matrix assembly IDA
 biological_processGO:1900106 positive regulation of hyaluranon cable assembly ISO
 cellular_componentGO:0005737 cytoplasm IDA
 cellular_componentGO:0005887 integral component of plasma membrane IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0036117 hyaluranon cable ISO
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0016757 transferase activity, transferring glycosyl groups IEA
 molecular_functionGO:0050501 hyaluronan synthase activity IEA


Pathways (from Reactome)
Pathway description
Hyaluronan biosynthesis and export


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0002133 abnormal respiratory system physiology "anomalous function of the pulmonary system; inability or reduced ability to intake and exchange oxygen and carbon dioxide with the environment" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Fbn1tm1Hcd/Fbn1+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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