Manteia

ENSMUSG00000004843

Mus musculus

Features

Gene ID:	ENSMUSG00000004843

Biological name :	Chmp2b

Synonyms :	Charged multivesicular body protein 2b / Chmp2b / Q8BJF9

Possible biological names infered from orthology :	Q9UQN3

Species:	Mus musculus

Chr. number:	16
Strand:	-1
Band:	C1.3
Gene start:	65539133
Gene end:	65562697

Corresponding Affymetrix probe sets:	10440307 (MoGene1.0st) 1428252_at (Mouse Genome 430 2.0 Array) 1428253_at (Mouse Genome 430 2.0 Array)

Cross references:	Ensembl peptide - ENSMUSP00000004965 NCBI entrez gene - 68942 See in Manteia. MGI - MGI:1916192 RefSeq - NM_026879 RefSeq Peptide - NP_081155 swissprot - Q8BJF9 Ensembl - ENSMUSG00000004843

See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed

Ortholog prediction (from Ensembl)

Paralog prediction (from Ensembl)

Paralog name	ID	Similarity(%)
Chmp2a / Q9DB34 / Charged multivesicular body protein 2a / O43633*	ENSMUSG00000033916	33

Protein motifs (from Interpro)

Interpro ID	Name
IPR005024	Snf7 family

Gene Ontology (GO)

Type	GO ID	Term	Ev.Code
biological_process	GO:0000920	cell separation after cytokinesis	IEA
biological_process	GO:0006997	nucleus organization	IEA
biological_process	GO:0007032	endosome organization	IEA
biological_process	GO:0007034	vacuolar transport	IEA
biological_process	GO:0007080	mitotic metaphase plate congression	IEA
biological_process	GO:0010824	regulation of centrosome duplication	IEA
biological_process	GO:0015031	protein transport	IEA
biological_process	GO:0039702	viral budding via host ESCRT complex	IEA
biological_process	GO:0050890	cognition	IEA
biological_process	GO:0070050	neuron cellular homeostasis	IEA
biological_process	GO:1901673	regulation of mitotic spindle assembly	IEA
biological_process	GO:1902188	positive regulation of viral release from host cell	IEA
cellular_component	GO:0000815	ESCRT III complex	IEA
cellular_component	GO:0005622	intracellular	IEA
cellular_component	GO:0005737	cytoplasm	IEA
cellular_component	GO:0005764	lysosome	IEA
cellular_component	GO:0005768	endosome	IEA
cellular_component	GO:0005770	late endosome	IEA
cellular_component	GO:0005829	cytosol	IEA
cellular_component	GO:0005886	plasma membrane	IEA
cellular_component	GO:0016020	membrane	IEA
cellular_component	GO:0031902	late endosome membrane	IEA
molecular_function	GO:0019904	protein domain specific binding	IEA
molecular_function	GO:0045296	cadherin binding	IEA

Pathways (from Reactome)

Pathway description

Macroautophagy

Phenotype (from MGI, Zfin or HPO)

ID	Phenotype	Definition	Genetic BG
MP:0008263	abnormal hippocampus CA1 region morphology		Show Allelic Composition: Gck^M1Btlr/Gck⁺ Genetic Background: C57BL/6J-Gck^M1Btlr
MP:0009538	abnormal synapse morphology	"any strucutral anomaly of the membrane junction site of a nerve cell to a target cell, such as another nerve cell, an effector cell, or a sensory receptor cell; transmission of nerve impulses may be mediated by chemical or by electrical means" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition", MESH:A08.850]	Show Allelic Composition: Gck^M1Btlr/Gck⁺ Genetic Background: C57BL/6J-Gck^M1Btlr
MP:0009936	abnormal dendritic spine morphology	"any structural anomaly of the small membranous protrusion from the dendrite of a neuron that is involved in synaptic transmission; it typically receives input from a single synapse of an axon" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"]	Show Allelic Composition: Gck^M1Btlr/Gck⁺ Genetic Background: C57BL/6J-Gck^M1Btlr

Interacting proteins (from Reactome)

Interactor ID

Name

Interaction type

No match

1 s.

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		© Olivier Tassy / Olivier Pourquie 2007-2024 contact: otassy@igbmc.fr