ENSMUSG00000004929


Mus musculus

Features
Gene ID: ENSMUSG00000004929
  
Biological name :Thop1
  
Synonyms : thimet oligopeptidase 1 / Thop1
  
Possible biological names infered from orthology : P52888
  
Species: Mus musculus
  
Chr. number: 10
Strand: 1
Band: C1
Gene start: 81070035
Gene end: 81082559
  
Corresponding Affymetrix probe sets: 10364955 (MoGene1.0st)   1425402_at (Mouse Genome 430 2.0 Array)   1448907_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000005057
NCBI entrez gene - 50492     See in Manteia.
MGI - MGI:1354165
RefSeq - NM_022653
RefSeq Peptide - NP_073144
swissprot - A0A0R4IZY0
Ensembl - ENSMUSG00000004929
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 thop1ENSDARG00000013776Danio rerio
 THOP1ENSGALG00000041934Gallus gallus
 THOP1ENSG00000172009Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Nln / Q91YP2 / Neurolysin, mitochondrial / Q9BYT8* / neurolysin*ENSMUSG0000002171062


Protein motifs (from Interpro)
Interpro ID Name
 IPR001567  Peptidase M3A/M3B catalytic domain
 IPR024080  Neurolysin/Thimet oligopeptidase, N-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006508 proteolysis IEA
 molecular_functionGO:0004222 metalloendopeptidase activity IEA
 molecular_functionGO:0008233 peptidase activity IEA
 molecular_functionGO:0008237 metallopeptidase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0042277 peptide binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Antigen processing: Ubiquitination & Proteasome degradation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr