Manteia

ENSMUSG00000005547

Mus musculus

Features

Gene ID:	ENSMUSG00000005547

Biological name :	Cyp2a5

Synonyms :	Cyp2a5

Possible biological names infered from orthology :	CYP2A13 / CYP2A6 / CYP2A7 / cytochrome P450 family 2 subfamily A member 13 / cytochrome P450 family 2 subfamily A member 6 / cytochrome P450 family 2 subfamily A member 7 / P11509 / P20853 / Q16696

Species:	Mus musculus

Chr. number:	7
Strand:	1
Band:	A3
Gene start:	26835305
Gene end:	26843548

Corresponding Affymetrix probe sets:	10551226 (MoGene1.0st) 1422230_s_at (Mouse Genome 430 2.0 Array)

Cross references:	Ensembl peptide - ENSMUSP00000127829 Ensembl peptide - ENSMUSP00000128865 Ensembl peptide - ENSMUSP00000130640 Ensembl peptide - ENSMUSP00000005685 NCBI entrez gene - 13087 See in Manteia. MGI - MGI:88597 RefSeq - NM_007812 RefSeq Peptide - NP_031838 swissprot - Q91X75 swissprot - E9Q5D4 swissprot - F6SHL3 swissprot - F7B9W9 Ensembl - ENSMUSG00000005547

See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed

Ortholog prediction (from Ensembl)

Ortholog name	ID	Species
CYP2C9	ENSDARG00000101423	Danio rerio
CYP2A6	ENSG00000255974	Homo sapiens
CYP2A7	ENSG00000198077	Homo sapiens
Q16696	ENSG00000197838	Homo sapiens

Paralog prediction (from Ensembl)

Paralog name	ID	Similarity(%)
P15392 / Cyp2a4 / Cytochrome P450 2A4 / P11509* / Q16696* / P20853* / CYP2A7* / CYP2A6* / CYP2A13* / cytochrome P450 family 2 subfamily A member 7* / cytochrome P450 family 2 subfamily A m...	ENSMUSG00000074254	98
P56593 / Cyp2a12 / Cytochrome P450 2A12	ENSMUSG00000060407	72
Cyp2a22 / cytochrome P450, family 2, subfamily a, polypeptide 22	ENSMUSG00000091867	71
Cyp2g1 / cytochrome P450, family 2, subfamily g, polypeptide 1	ENSMUSG00000049685	58
O55071 / Cyp2b19 / Cytochrome P450 2B19 / P20813* / CYP2B6* / cytochrome P450 family 2 subfamily B member 6*	ENSMUSG00000066704	53
Cyp2b10 / CYP2B6* / P20813* / cytochrome P450 family 2 subfamily B member 6*	ENSMUSG00000030483	53
Cyp2b23 / cytochrome P450, family 2, subfamily b, polypeptide 23 / CYP2B6* / P20813* / cytochrome P450 family 2 subfamily B member 6*	ENSMUSG00000040650	52
Cyp2c65 / cytochrome P450, family 2, subfamily c, polypeptide 65 / CYP2C9* / P33261* / P11712* / P10632* / CYP2C8* / CYP2C19* / cytochrome P450 family 2 subfamily C member 9* / cytochrome P...	ENSMUSG00000067231	52
Cyp2b13 / cytochrome P450, family 2, subfamily b, polypeptide 13 / CYP2B6* / P20813* / cytochrome P450 family 2 subfamily B member 6*	ENSMUSG00000040583	51
Cyp2c66 / cytochrome P450, family 2, subfamily c, polypeptide 66 / CYP2C9* / P33261* / P11712* / P10632* / CYP2C8* / CYP2C19* / cytochrome P450 family 2 subfamily C member 9* / cytochrome P...	ENSMUSG00000067229	51
P33267 / Cyp2f2 / Cytochrome P450 2F2 / CYP2F1* / P24903* / cytochrome P450 family 2 subfamily F member 1*	ENSMUSG00000052974	51
Q64458 / Cyp2c29 / Cytochrome P450 2C29 / P10632* / CYP2C9* / P33261* / P11712* / CYP2C8* / CYP2C19* / cytochrome P450 family 2 subfamily C member 9* / cytochrome P450 family 2 subfamily C...	ENSMUSG00000003053	50
P56654 / Cyp2c37 / Cytochrome P450 2C37 / P10632* / CYP2C9* / P33261* / P11712* / CYP2C8* / CYP2C19* / cytochrome P450 family 2 subfamily C member 9* / cytochrome P450 family 2 subfamily C...	ENSMUSG00000042248	50
P56656 / Cyp2c39 / Cytochrome P450 2C39 / P10632* / CYP2C9* / P33261* / P11712* / CYP2C8* / CYP2C19* / cytochrome P450 family 2 subfamily C member 9* / cytochrome P450 family 2 subfamily C...	ENSMUSG00000025003	50
P56655 / Cyp2c38 / Cytochrome P450 2C38 / P10632* / CYP2C9* / P33261* / P11712* / CYP2C8* / CYP2C19* / cytochrome P450 family 2 subfamily C member 9* / cytochrome P450 family 2 subfamily C...	ENSMUSG00000032808	50
Q91X77 / Cyp2c50 / Cytochrome P450 2C50 / P10632* / CYP2C9* / P33261* / P11712* / CYP2C8* / CYP2C19* / cytochrome P450 family 2 subfamily C member 9* / cytochrome P450 family 2 subfamily C...	ENSMUSG00000054827	50
Cyp2c23 / cytochrome P450, family 2, subfamily c, polypeptide 23	ENSMUSG00000025197	50
Cyp2b9 / P12790 / Cytochrome P450 2B9 / P20813* / CYP2B6* / cytochrome P450 family 2 subfamily B member 6*	ENSMUSG00000040660	50
Q9D816 / Cyp2c55 / Cytochrome P450 2C55 / P33260* / CYP2C18* / AL583836.1* / cytochrome P450 family 2 subfamily C member 18*	ENSMUSG00000025002	49
Q6XVG2 / Cyp2c54 / Cytochrome P450 2C54 / P10632* / CYP2C9* / P33261* / P11712* / CYP2C8* / CYP2C19* / cytochrome P450 family 2 subfamily C member 9* / cytochrome P450 family 2 subfamily C...	ENSMUSG00000067225	49

Protein motifs (from Interpro)

Interpro ID	Name
IPR001128	Cytochrome P450
IPR002401	Cytochrome P450, E-class, group I
IPR008067	Cytochrome P450, E-class, group I, CYP2A-like
IPR017972	Cytochrome P450, conserved site
IPR036396	Cytochrome P450 superfamily

Gene Ontology (GO)

Type	GO ID	Term	Ev.Code
biological_process	GO:0055114	oxidation-reduction process	IEA
cellular_component	GO:0016020	membrane	IEA
cellular_component	GO:0016021	integral component of membrane	IEA
molecular_function	GO:0004497	monooxygenase activity	IEA
molecular_function	GO:0005506	iron ion binding	IEA
molecular_function	GO:0016491	oxidoreductase activity	IEA
molecular_function	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen	IEA
molecular_function	GO:0016712	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen	IEA
molecular_function	GO:0020037	heme binding	IEA
molecular_function	GO:0046872	metal ion binding	IEA

Pathways (from Reactome)

Pathway description

Fatty acids

Xenobiotics

CYP2E1 reactions

Aflatoxin activation and detoxification

Phenotype (from MGI, Zfin or HPO)

ID	Phenotype	Definition	Genetic BG
MP:0008875	abnormal pharmacokinetics of xenobiotics	"any anomaly in the absorbtion, distribution, metabolism or elimination of a foreign compound" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]	Show Allelic Composition: Aplp2^tm1Dbo/Aplp2^tm1Dbo,App^tm1.2Zhe/App^tm2.1Zhe Genetic Background: involves: 129S1/Sv * 129S7/SvEvBrd * 129X1/SvJ

Interacting proteins (from Reactome)

Interactor ID

Name

Interaction type

No match

1 s.

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		© Olivier Tassy / Olivier Pourquie 2007-2024 contact: otassy@igbmc.fr