ENSDARG00000101423


Danio rerio

Features
Gene ID: ENSDARG00000101423
  
Biological name :CYP2C9
  
Synonyms : CYP2C9 / cyp2y3 / si:zfos-411a11.2
  
Possible biological names infered from orthology : AL583836.1 / Cyp2a12 / CYP2A13 / Cyp2a22 / Cyp2a4 / Cyp2a5 / CYP2A6 / CYP2A7 / Cyp2b10 / Cyp2b13 / Cyp2b19 / Cyp2b23 / CYP2B6 / Cyp2b9 / CYP2C18 / CYP2C19 / Cyp2c23 / Cyp2c29 / Cyp2c37 / Cyp2c38 / Cyp2c39 / Cyp2c40 / Cyp2c50 / Cyp2c54 / Cyp2c55 / Cyp2c65 / Cyp2c66 / Cyp2c70 / CYP2C8 / CYP2E1 / CYP2F1 / Cyp2f2 / Cyp2g1 / Cytochrome P450 2A12 / Cytochrome P450 2A4 / Cytochrome P450 2B19 / Cytochrome P450 2B9 / Cytochrome P450 2C29 / Cytochrome P450 2C37 / Cytochrome P450 2C38 / Cytochrome P450 2C39 / Cytochrome P450 2C50 / Cytochrome P450 2C54 / Cytochrome P450 2C55 / Cytochrome P450 2C70 / Cytochrome P450 2E1 / Cytochrome P450 2F2 / cytochrome P450 family 2 subfamily A member 13 / cytochrome P450 family 2 subfamily A member 6 / cytochrome P450 family 2 subfamily A member 7 / cytochrome P450, family 2, subfamily a, polypeptide 22 / cytochrome P450 family 2 subfamily B member 6 / cytochrome P450, family 2, subfamily b, polypeptide 13 / cytochrome P450, family 2, subfamily b, polypeptide 23 / cytochrome P450 family 2 subfamily C member 18 / cytochrome P450 family 2 subfamily C member 19 / cytochrome P450 family 2 subfamily C member 8 / cytochrome P450 family 2 subfamily C member 9 / cytochrome P450, family 2, subfamily c, polypeptide 23 / cytochrome P450, family 2, subfamily c, polypeptide 65 / cytochrome P450, family 2, subfamily c, polypeptide 66 / cytochrome P450 family 2 subfamily E member 1 / cytochrome P450 family 2 subfamily F member 1 / cytochrome P450, family 2, subfamily g, polypeptide 1 / O55071 / P05181 / P10632 / P11509 / P11712 / P12790 / P15392 / P20813 / P20853 / P24903 / P33260 / P33261 / P33267 / P56593 / P56654 / P56655 / P56656 / Q05421 / Q16696 / Q64458 / Q6XVG2 / Q91W64 / Q91X77 / Q9D816
  
Species: Danio rerio
  
Chr. number: 15
Strand: -1
Band:
Gene start: 16175
Gene end: 32151
  
Corresponding Affymetrix probe sets: DrAffx.2.104.A1_at (Zebrafish Array)   DrAffx.2.104.S1_at (Zebrafish Array)   DrAffx.2.76.A1_at (Zebrafish Array)   NM_001020822_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000089848
Ensembl peptide - ENSDARP00000135608
NCBI entrez gene - 368352     See in Manteia.
RefSeq - NM_001020822
RefSeq Peptide - NP_001018658
swissprot - E7F1Y3
swissprot - A0A0R4IKH1
ZFIN ID - ZDB-GENE-050522-490
ZFIN ID - ZDB-GENE-131119-33
Ensembl - ENSDARG00000101423
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CYP2C23bENSGALG00000005795Gallus gallus
 CYP2C45ENSGALG00000023925Gallus gallus
 AL583836.1ENSG00000276490Homo sapiens
 CYP2A6ENSG00000255974Homo sapiens
 CYP2A7ENSG00000198077Homo sapiens
 CYP2B6ENSG00000197408Homo sapiens
 CYP2C8ENSG00000138115Homo sapiens
 CYP2C9ENSG00000138109Homo sapiens
 CYP2E1ENSG00000130649Homo sapiens
 CYP2F1ENSG00000197446Homo sapiens
 P33260ENSG00000108242Homo sapiens
 P33261ENSG00000165841Homo sapiens
 Q16696ENSG00000197838Homo sapiens
 Cyp2a22ENSMUSG00000091867Mus musculus
 Cyp2a4ENSMUSG00000074254Mus musculus
 Cyp2a5ENSMUSG00000005547Mus musculus
 Cyp2b10ENSMUSG00000030483Mus musculus
 Cyp2b13ENSMUSG00000040583Mus musculus
 Cyp2b23ENSMUSG00000040650Mus musculus
 Cyp2b9ENSMUSG00000040660Mus musculus
 Cyp2c23ENSMUSG00000025197Mus musculus
 Cyp2c40ENSMUSG00000025004Mus musculus
 Cyp2c65ENSMUSG00000067231Mus musculus
 Cyp2c66ENSMUSG00000067229Mus musculus
 Cyp2e1ENSMUSG00000025479Mus musculus
 Cyp2f2ENSMUSG00000052974Mus musculus
 Cyp2g1ENSMUSG00000049685Mus musculus
 O55071ENSMUSG00000066704Mus musculus
 P56593ENSMUSG00000060407Mus musculus
 P56654ENSMUSG00000042248Mus musculus
 P56655ENSMUSG00000032808Mus musculus
 P56656ENSMUSG00000025003Mus musculus
 Q64458ENSMUSG00000003053Mus musculus
 Q6XVG2ENSMUSG00000067225Mus musculus
 Q91W64ENSMUSG00000060613Mus musculus
 Q91X77ENSMUSG00000054827Mus musculus
 Q9D816ENSMUSG00000025002Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR001128  Cytochrome P450
 IPR002401  Cytochrome P450, E-class, group I
 IPR008067  Cytochrome P450, E-class, group I, CYP2A-like
 IPR017972  Cytochrome P450, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0019369 arachidonic acid metabolic process IBA
 biological_processGO:0055114 oxidation-reduction process IEA
 molecular_functionGO:0004497 monooxygenase activity IEA
 molecular_functionGO:0005506 iron ion binding IEA
 molecular_functionGO:0008395 steroid hydroxylase activity IBA
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen IEA
 molecular_functionGO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen IEA
 molecular_functionGO:0020037 heme binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Fatty acids
Xenobiotics
CYP2E1 reactions
Synthesis of epoxy (EET) and dihydroxyeicosatrienoic acids (DHET)
Synthesis of (16-20)-hydroxyeicosatetraenoic acids (HETE)
Aflatoxin activation and detoxification
Biosynthesis of maresin-like SPMs


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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