ENSG00000197446


Homo sapiens

Features
Gene ID: ENSG00000197446
  
Biological name :CYP2F1
  
Synonyms : CYP2F1 / cytochrome P450 family 2 subfamily F member 1 / P24903
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 19
Strand: 1
Band: q13.2
Gene start: 41114432
Gene end: 41128366
  
Corresponding Affymetrix probe sets: 207913_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000471416
Ensembl peptide - ENSP00000333534
Ensembl peptide - ENSP00000443424
Ensembl peptide - ENSP00000470136
NCBI entrez gene - 1572     See in Manteia.
OMIM - 124070
RefSeq - XM_017026385
RefSeq - XM_011526553
RefSeq - XM_011526554
RefSeq - XM_011526555
RefSeq - XM_017026384
RefSeq - NM_000774
RefSeq - XM_011526551
RefSeq - XM_011526552
RefSeq Peptide - NP_000765
swissprot - H0YGI9
swissprot - A0A075B795
swissprot - P24903
Ensembl - ENSG00000197446
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CYP2C9ENSDARG00000101423Danio rerio
 Cyp2f2ENSMUSG00000052974Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
CYP2A6 / P11509 / cytochrome P450 family 2 subfamily A member 6ENSG0000025597453
P33260 / CYP2C18 / cytochrome P450 family 2 subfamily C member 18ENSG0000010824252
Q16696 / CYP2A13 / cytochrome P450 family 2 subfamily A member 13ENSG0000019783852
P33261 / CYP2C19 / cytochrome P450 family 2 subfamily C member 19ENSG0000016584151
CYP2A7 / P20853 / cytochrome P450 family 2 subfamily A member 7ENSG0000019807750
CYP2C9 / P11712 / cytochrome P450 family 2 subfamily C member 9ENSG0000013810950
CYP2C8 / P10632 / cytochrome P450 family 2 subfamily C member 8ENSG0000013811550
CYP2E1 / P05181 / cytochrome P450 family 2 subfamily E member 1ENSG0000013064948
CYP2B6 / P20813 / cytochrome P450 family 2 subfamily B member 6ENSG0000019740848
AL583836.1ENSG0000027649033


Protein motifs (from Interpro)
Interpro ID Name
 IPR001128  Cytochrome P450
 IPR002401  Cytochrome P450, E-class, group I
 IPR017972  Cytochrome P450, conserved site
 IPR020469  Cytochrome P450, CYP2 family
 IPR036396  Cytochrome P450 superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006805 xenobiotic metabolic process TAS
 biological_processGO:0009636 response to toxic substance IEA
 biological_processGO:0018931 naphthalene metabolic process IDA
 biological_processGO:0018979 trichloroethylene metabolic process IEA
 biological_processGO:0019373 epoxygenase P450 pathway IBA
 biological_processGO:0055114 oxidation-reduction process IEA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005789 endoplasmic reticulum membrane TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0031090 organelle membrane IEA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IEA
 molecular_functionGO:0004497 monooxygenase activity TAS
 molecular_functionGO:0005506 iron ion binding IEA
 molecular_functionGO:0008392 arachidonic acid epoxygenase activity IBA
 molecular_functionGO:0008395 steroid hydroxylase activity IBA
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen IEA
 molecular_functionGO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen IDA
 molecular_functionGO:0019825 oxygen binding TAS
 molecular_functionGO:0020037 heme binding IEA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0070330 aromatase activity IEA


Pathways (from Reactome)
Pathway description
Fatty acids
Xenobiotics
CYP2E1 reactions


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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