ENSG00000108242


Homo sapiens

Features
Gene ID: ENSG00000108242
  
Biological name :CYP2C18
  
Synonyms : CYP2C18 / cytochrome P450 family 2 subfamily C member 18 / P33260
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 10
Strand: 1
Band: q23.33
Gene start: 94683621
Gene end: 94736190
  
Corresponding Affymetrix probe sets: 208126_s_at (Human Genome U133 Plus 2.0 Array)   215103_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000285979
Ensembl peptide - ENSP00000341293
NCBI entrez gene - 1562     See in Manteia.
OMIM - 601131
RefSeq - NM_000772
RefSeq - NM_001128925
RefSeq Peptide - NP_000763
RefSeq Peptide - NP_001122397
swissprot - P33260
Ensembl - ENSG00000108242
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CYP2C9ENSDARG00000101423Danio rerio
 CYP2C23bENSGALG00000005795Gallus gallus
 CYP2C45ENSGALG00000023925Gallus gallus
 Q9D816ENSMUSG00000025002Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
CYP2C9 / P11712 / cytochrome P450 family 2 subfamily C member 9ENSG0000013810982
P33261 / CYP2C19 / cytochrome P450 family 2 subfamily C member 19ENSG0000016584181
CYP2C8 / P10632 / cytochrome P450 family 2 subfamily C member 8ENSG0000013811577
AL583836.1ENSG0000027649064
CYP2E1 / P05181 / cytochrome P450 family 2 subfamily E member 1ENSG0000013064957
CYP2F1 / P24903 / cytochrome P450 family 2 subfamily F member 1ENSG0000019744652
Q16696 / CYP2A13 / cytochrome P450 family 2 subfamily A member 13ENSG0000019783850
CYP2A7 / P20853 / cytochrome P450 family 2 subfamily A member 7ENSG0000019807749
CYP2A6 / P11509 / cytochrome P450 family 2 subfamily A member 6ENSG0000025597449
CYP2B6 / P20813 / cytochrome P450 family 2 subfamily B member 6ENSG0000019740848


Protein motifs (from Interpro)
Interpro ID Name
 IPR001128  Cytochrome P450
 IPR002401  Cytochrome P450, E-class, group I
 IPR017972  Cytochrome P450, conserved site
 IPR036396  Cytochrome P450 superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006805 xenobiotic metabolic process TAS
 biological_processGO:0019373 epoxygenase P450 pathway IBA
 biological_processGO:0055114 oxidation-reduction process IEA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005789 endoplasmic reticulum membrane TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0031090 organelle membrane IEA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IEA
 molecular_functionGO:0004497 monooxygenase activity TAS
 molecular_functionGO:0005506 iron ion binding IEA
 molecular_functionGO:0008392 arachidonic acid epoxygenase activity IBA
 molecular_functionGO:0008395 steroid hydroxylase activity IBA
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen IEA
 molecular_functionGO:0019825 oxygen binding TAS
 molecular_functionGO:0020037 heme binding IEA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0070330 aromatase activity IEA


Pathways (from Reactome)
Pathway description
Xenobiotics


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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