ENSMUSG00000006599


Mus musculus

Features
Gene ID: ENSMUSG00000006599
  
Biological name :Gtf2h1
  
Synonyms : general transcription factor IIH subunit 1 / Gtf2h1
  
Possible biological names infered from orthology : P32780
  
Species: Mus musculus
  
Chr. number: 7
Strand: 1
Band: B3
Gene start: 46796103
Gene end: 46823800
  
Corresponding Affymetrix probe sets: 10553280 (MoGene1.0st)   1453169_a_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000006774
Ensembl peptide - ENSMUSP00000129337
Ensembl peptide - ENSMUSP00000120008
Ensembl peptide - ENSMUSP00000103271
NCBI entrez gene - 14884     See in Manteia.
MGI - MGI:1277216
RefSeq - XM_006540636
RefSeq - NM_001291075
RefSeq - NM_008186
RefSeq Peptide - NP_032212
RefSeq Peptide - NP_001278004
swissprot - E9PWY2
swissprot - E9QKD9
swissprot - D6RJL7
swissprot - G3X8R4
Ensembl - ENSMUSG00000006599
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 gtf2h1ENSDARG00000026701Danio rerio
 GTF2H1ENSGALG00000042340Gallus gallus
 GTF2H1ENSG00000110768Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR005607  BSD domain
 IPR011993  PH-like domain superfamily
 IPR013876  TFIIH p62 subunit, N-terminal
 IPR027079  TFIIH subunit Tfb1/GTF2H1
 IPR035925  BSD domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006289 nucleotide-excision repair IEA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006366 transcription by RNA polymerase II IEA
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IEA
 cellular_componentGO:0000439 core TFIIH complex IEA
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005675 holo TFIIH complex IEA
 molecular_functionGO:0003682 chromatin binding IEA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0008094 DNA-dependent ATPase activity IEA
 molecular_functionGO:0008353 RNA polymerase II carboxy-terminal domain kinase activity IEA


Pathways (from Reactome)
Pathway description
Formation of RNA Pol II elongation complex
Formation of the Early Elongation Complex
Formation of Incision Complex in GG-NER
Dual Incision in GG-NER
RNA Polymerase II Pre-transcription Events
Formation of TC-NER Pre-Incision Complex
Dual incision in TC-NER
Gap-filling DNA repair synthesis and ligation in TC-NER
TP53 Regulates Transcription of DNA Repair Genes
mRNA Capping
RNA Polymerase I Transcription Initiation
RNA Polymerase I Promoter Escape
RNA Polymerase II Promoter Escape
RNA Polymerase I Chain Elongation
RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
RNA Polymerase I Transcription Termination
RNA Polymerase II Transcription Initiation
RNA Polymerase II Transcription Elongation
RNA Polymerase II Transcription Initiation And Promoter Clearance
RNA Pol II CTD phosphorylation and interaction with CE


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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