ENSMUSG00000006711


Mus musculus

Features
Gene ID: ENSMUSG00000006711
  
Biological name :D130043K22Rik
  
Synonyms : D130043K22Rik / Dyslexia-associated / Q5SZV5
  
Possible biological names infered from orthology : KIAA0319 / Q5VV43
  
Species: Mus musculus
  
Chr. number: 13
Strand: 1
Band: A3.1
Gene start: 24845135
Gene end: 24901270
  
Corresponding Affymetrix probe sets: 10404195 (MoGene1.0st)   1443327_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000006893
Ensembl peptide - ENSMUSP00000116004
NCBI entrez gene - 210108     See in Manteia.
MGI - MGI:3036268
RefSeq - NM_001081051
RefSeq Peptide - NP_001074520
swissprot - F2Z497
swissprot - Q5SZV5
Ensembl - ENSMUSG00000006711
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 KIAA0319ENSGALG00000041273Gallus gallus
 Q5VV43ENSG00000137261Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q8K135 / AU040320 / Dyslexia-associated protein KIAA0319-like protein / Q8IZA0* / KIAA0319L* / KIAA0319 like*ENSMUSG0000002883042
Lrp11 / Q8CB67 / Low-density lipoprotein receptor-related protein 11 / Q86VZ4* / LDL receptor related protein 11*ENSMUSG000000197966


Protein motifs (from Interpro)
Interpro ID Name
 IPR000601  PKD domain
 IPR002859  PKD/REJ-like domain
 IPR011106  Seven cysteines, N-terminal
 IPR013783  Immunoglobulin-like fold
 IPR013980  MANSC domain
 IPR022409  PKD/Chitinase domain
 IPR035986  PKD domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001764 neuron migration IEA
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0007399 nervous system development IEA
 biological_processGO:2000171 negative regulation of dendrite development IEA
 cellular_componentGO:0005768 endosome IEA
 cellular_componentGO:0005769 early endosome IEA
 cellular_componentGO:0005886 plasma membrane ISO
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0031901 early endosome membrane IEA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IEA
 molecular_functionGO:0003674 molecular_function ND


Pathways (from Reactome)
Pathway description
Cargo recognition for clathrin-mediated endocytosis
Clathrin-mediated endocytosis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001364 decreased anxiety-related response "when compared to controls, subjects exhibit fewer responses thought to be indicative of anxiety in behavioral tests" [cwg:Carroll-Ann W. Goldsmith, Mouse Genome Informatics curator, J:86626, J:85438, J:64043]
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Allelic Composition: Gt(ROSA)26Sortm3(Irf4)Evdr/Gt(ROSA)26Sor+,Tg(Ucp1-cre)1Evdr/0
Genetic Background: involves: 129 * C57BL/6J * FVB

 MP:0009141 increased prepulse inhibition "increase in the ability of a relatively mild stimulus to suppress the response to a strong, startle-eliciting stimulus" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
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Allelic Composition: Gt(ROSA)26Sortm3(Irf4)Evdr/Gt(ROSA)26Sor+,Tg(Ucp1-cre)1Evdr/0
Genetic Background: involves: 129 * C57BL/6J * FVB

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000006711 Q5SZV5 / D130043K22Rik / Dyslexia-associated / Q5VV43* / KIAA0319*  / complex






 

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