ENSMUSG00000010086


Mus musculus

Features
Gene ID: ENSMUSG00000010086
  
Biological name :Rnf112
  
Synonyms : Q96DY5 / RING finger protein 112 / Rnf112
  
Possible biological names infered from orthology : Q9ULX5
  
Species: Mus musculus
  
Chr. number: 11
Strand: -1
Band: B2
Gene start: 61448442
Gene end: 61454131
  
Corresponding Affymetrix probe sets: 10386705 (MoGene1.0st)   1418360_at (Mouse Genome 430 2.0 Array)   1456108_x_at (Mouse Genome 430 2.0 Array)   1460385_a_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000056464
Ensembl peptide - ENSMUSP00000059903
Ensembl peptide - ENSMUSP00000099722
NCBI entrez gene - 22671     See in Manteia.
MGI - MGI:106611
RefSeq - XM_017314505
RefSeq - NM_001291024
RefSeq - NM_009548
RefSeq - XM_006533184
RefSeq - XM_006533185
RefSeq - XM_017314504
RefSeq - XM_006533178
RefSeq - XM_006533179
RefSeq - XM_006533180
RefSeq - XM_006533181
RefSeq - XM_006533182
RefSeq - XM_006533183
RefSeq Peptide - NP_033574
RefSeq Peptide - NP_001277953
swissprot - Q96DY5
Ensembl - ENSMUSG00000010086
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Q9ULX5ENSG00000128482Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Atl3 / Q91YH5 / Atlastin-3 / Q6DD88* / atlastin GTPase 3*ENSMUSG0000002475917
Atl2 / Q6PA06 / Mus musculus atlastin GTPase 2 (Atl2), transcript variant 5, mRNA. / Q8NHH9* / atlastin GTPase 2*ENSMUSG0000005981116
Atl1 / Q8BH66 / Atlastin-1 / Q8WXF7* / atlastin GTPase 1*ENSMUSG0000002106616


Protein motifs (from Interpro)
Interpro ID Name
 IPR001841  Zinc finger, RING-type
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR015894  Guanylate-binding protein, N-terminal
 IPR018957  Zinc finger, C3HC4 RING-type
 IPR027417  P-loop containing nucleoside triphosphate hydrolase
 IPR030386  GB1/RHD3-type guanine nucleotide-binding (G) domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0045666 positive regulation of neuron differentiation IMP
 biological_processGO:0045687 positive regulation of glial cell differentiation IMP
 biological_processGO:0071158 positive regulation of cell cycle arrest IMP
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0003674 molecular_function ND
 molecular_functionGO:0003924 GTPase activity IEA
 molecular_functionGO:0005525 GTP binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000774 reduced brain size "smaller appearance of the brain" [J:35802]
Show

Allelic Composition: Ehmt1tm1Bzhu/Ehmt1tm1Bzhu,Ehmt2tm1Bzhu/Ehmt2tm1Bzhu
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

 MP:0001919 abnormal reproductive system physiology "anomaly in the function of the organs associated with producing offspring " [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Ehmt1tm1Bzhu/Ehmt1tm1Bzhu,Ehmt2tm1Bzhu/Ehmt2tm1Bzhu
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

 MP:0002920 reduced paired-pulse facilitation "decrease in the response of central synapses when activated twice in rapid succession; indicative of defects in short-term plasticity due to lack of increase of neurotransmitter release at the second stimulus" [Principles of Neural Science , 3rd edition:ISBN 0-8385-8034-3]
Show

Allelic Composition: Ehmt1tm1Bzhu/Ehmt1tm1Bzhu,Ehmt2tm1Bzhu/Ehmt2tm1Bzhu
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

 MP:0004753 abnormal miniature excitatory postsynaptic currents "defect in the size or duration of spontaneous currents detected in postsynaptic cells that occur in the absence of an excitatory impulse" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Ehmt1tm1Bzhu/Ehmt1tm1Bzhu,Ehmt2tm1Bzhu/Ehmt2tm1Bzhu
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

 MP:0009936 abnormal dendritic spine morphology "any structural anomaly of the small membranous protrusion from the dendrite of a neuron that is involved in synaptic transmission; it typically receives input from a single synapse of an axon" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Ehmt1tm1Bzhu/Ehmt1tm1Bzhu,Ehmt2tm1Bzhu/Ehmt2tm1Bzhu
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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