ENSMUSG00000059811


Mus musculus

Features
Gene ID: ENSMUSG00000059811
  
Biological name :Atl2
  
Synonyms : Atl2 / Mus musculus atlastin GTPase 2 (Atl2), transcript variant 5, mRNA. / Q6PA06
  
Possible biological names infered from orthology : atlastin GTPase 2 / Q8NHH9
  
Species: Mus musculus
  
Chr. number: 17
Strand: -1
Band: E3
Gene start: 79848390
Gene end: 79896123
  
Corresponding Affymetrix probe sets: 10453062 (MoGene1.0st)   1416793_at (Mouse Genome 430 2.0 Array)   1416794_at (Mouse Genome 430 2.0 Array)   1431197_at (Mouse Genome 430 2.0 Array)   1435594_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000152340
Ensembl peptide - ENSMUSP00000152866
Ensembl peptide - ENSMUSP00000064758
Ensembl peptide - ENSMUSP00000108056
NCBI entrez gene - 56298     See in Manteia.
MGI - MGI:1929492
RefSeq - XM_017317584
RefSeq - NM_001357753
RefSeq - NM_019717
RefSeq - NM_178050
RefSeq - XM_006524653
RefSeq - XM_006524654
RefSeq - XM_006524655
RefSeq - XM_006524656
RefSeq - XM_006524657
RefSeq - NM_001286647
RefSeq Peptide - NP_062691
RefSeq Peptide - NP_835151
RefSeq Peptide - NP_001273576
RefSeq Peptide - NP_001344682
swissprot - Q6PA06
swissprot - A0A1Y7VKB0
swissprot - E9QND8
swissprot - A0A1Y7VJ85
Ensembl - ENSMUSG00000059811
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 atl2ENSDARG00000057719Danio rerio
 ATL2ENSGALG00000037289Gallus gallus
 ATL2ENSG00000119787Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Atl1 / Q8BH66 / Atlastin-1 / Q8WXF7* / atlastin GTPase 1*ENSMUSG0000002106661
Atl3 / Q91YH5 / Atlastin-3 / Q6DD88* / atlastin GTPase 3*ENSMUSG0000002475958
Q96DY5 / Rnf112 / RING finger protein 112 / Q9ULX5*ENSMUSG0000001008618


Protein motifs (from Interpro)
Interpro ID Name
 IPR003191  Guanylate-binding protein/Atlastin, C-terminal
 IPR015894  Guanylate-binding protein, N-terminal
 IPR027417  P-loop containing nucleoside triphosphate hydrolase
 IPR030386  GB1/RHD3-type guanine nucleotide-binding (G) domain
 IPR036543  Guanylate-binding protein, C-terminal domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007029 endoplasmic reticulum organization IEA
 biological_processGO:0007030 Golgi organization IEA
 biological_processGO:0051260 protein homooligomerization IEA
 biological_processGO:1990809 endoplasmic reticulum tubular network membrane organization IEA
 cellular_componentGO:0005783 endoplasmic reticulum ISO
 cellular_componentGO:0005789 endoplasmic reticulum membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0098826 endoplasmic reticulum tubular network membrane IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003924 GTPase activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005525 GTP binding IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0042802 identical protein binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0004953 decreased spleen weight "reduction in the average weight of the organ that functions to filter blood and to store red corpuscles and platelets" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Aspatm1b(EUCOMM)Wtsi/Aspatm1b(EUCOMM)Wtsi
Genetic Background: C57BL/6N-Aspatm1b(EUCOMM)Wtsi/Ieg

 MP:0005564 increased hemoglobin content "increase in the total hemoglobin content in the circulating blood" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, RGD:Rat Genome Database submission]
Show

Allelic Composition: Aspatm1b(EUCOMM)Wtsi/Aspatm1b(EUCOMM)Wtsi
Genetic Background: C57BL/6N-Aspatm1b(EUCOMM)Wtsi/Ieg

 MP:0010024 increased total body fat amount "greater than the normal total amount of connective tissue composed of fat cells within the entire body" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Aspatm1b(EUCOMM)Wtsi/Aspatm1b(EUCOMM)Wtsi
Genetic Background: C57BL/6N-Aspatm1b(EUCOMM)Wtsi/Ieg

 MP:0011100 complete preweaning lethality "death of all organisms of a given genotype in a population between fertilization and weaning age (Mus: approximately 3-4 weeks of age)" [MGI:csmith]
Show

Allelic Composition: Arf4tm1b(KOMP)Wtsi/Arf4tm1b(KOMP)Wtsi
Genetic Background: C57BL/6N-Arf4tm1b(KOMP)Wtsi/Ucd

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr