ENSMUSG00000013878


Mus musculus

Features
Gene ID: ENSMUSG00000013878
  
Biological name :Rnf170
  
Synonyms : Mus musculus ring finger protein 170 (Rnf170), transcript variant 3, mRNA. / Q8CBG9 / Rnf170
  
Possible biological names infered from orthology : Q96K19 / ring finger protein 170
  
Species: Mus musculus
  
Chr. number: 8
Strand: 1
Band: A2
Gene start: 26119368
Gene end: 26151790
  
Corresponding Affymetrix probe sets: 10551215 (MoGene1.0st)   10571093 (MoGene1.0st)   1431195_at (Mouse Genome 430 2.0 Array)   1434956_at (Mouse Genome 430 2.0 Array)   1437207_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000118689
Ensembl peptide - ENSMUSP00000119906
Ensembl peptide - ENSMUSP00000147842
Ensembl peptide - ENSMUSP00000147376
Ensembl peptide - ENSMUSP00000014022
Ensembl peptide - ENSMUSP00000106204
Ensembl peptide - ENSMUSP00000106208
Ensembl peptide - ENSMUSP00000115588
Ensembl peptide - ENSMUSP00000115959
NCBI entrez gene - 77733     See in Manteia.
MGI - MGI:1924983
RefSeq - XM_006509216
RefSeq - XM_006509218
RefSeq - XM_006509217
RefSeq - XM_006509215
RefSeq - NM_001357293
RefSeq - NM_001357294
RefSeq - NM_001357295
RefSeq - NM_029965
RefSeq - XM_006509221
RefSeq Peptide - NP_001344223
RefSeq Peptide - NP_001344222
RefSeq Peptide - NP_001344224
RefSeq Peptide - NP_084241
swissprot - Q8CBG9
swissprot - E9PUJ5
swissprot - A0A1B0GR51
swissprot - F6UDR6
swissprot - D3Z7W3
Ensembl - ENSMUSG00000013878
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 rnf170ENSDARG00000104069Danio rerio
 RNF170ENSGALG00000015386Gallus gallus
 Q96K19ENSG00000120925Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Gm45692 / Q96K19* / RNF170* / ring finger protein 170*ENSMUSG0000010985049


Protein motifs (from Interpro)
Interpro ID Name
 IPR001841  Zinc finger, RING-type
 IPR010652  Domain of unknown function DUF1232
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR017907  Zinc finger, RING-type, conserved site
 IPR018957  Zinc finger, C3HC4 RING-type


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0008150 biological_process ND
 biological_processGO:0016567 protein ubiquitination IEA
 cellular_componentGO:0005575 cellular_component ND
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005789 endoplasmic reticulum membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0003674 molecular_function ND
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001406 abnormal gait "unusual or distinctive way of walking" [J:65038]
Show

Allelic Composition: Mdm4tm2Glo/Mdm4tm2.1Glo,Tg(Myh6-cre)2182Mds/0,Trp53tm1Tyj/Trp53tm1Brn
Genetic Background: involves: 129P2/OlaHsd * 129S2/SvPas * 129S4/SvJaeSor * 129S7/SvEvBrd * C57BL/6J * FVB/N

 MP:0001524 impaired limb coordination "reduced ability to organize limb movements to execute complex maneuvers, such as walking" [J:64962, MGI:CLS, J:17123]
Show

Allelic Composition: Mdm4tm2Glo/Mdm4tm2.1Glo,Tg(Myh6-cre)2182Mds/0,Trp53tm1Tyj/Trp53tm1Brn
Genetic Background: involves: 129P2/OlaHsd * 129S2/SvPas * 129S4/SvJaeSor * 129S7/SvEvBrd * C57BL/6J * FVB/N

 MP:0001973 increased thermal nociceptive threshold "a greater than average point at which thermal pain sensation is first detectable" [What s Wrong With My Mouse?:ISBN 0-471-31639-3, J:17194]
Show

Allelic Composition: Mdm4tm2Glo/Mdm4tm2.1Glo,Tg(Myh6-cre)2182Mds/0,Trp53tm1Tyj/Trp53tm1Brn
Genetic Background: involves: 129P2/OlaHsd * 129S2/SvPas * 129S4/SvJaeSor * 129S7/SvEvBrd * C57BL/6J * FVB/N

 MP:0002106 abnormal muscle physiology "anomolous function of the muscle, not due to an anatomical defect" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Mdm4tm2Glo/Mdm4tm2.1Glo,Tg(Myh6-cre)2182Mds/0,Trp53tm1Tyj/Trp53tm1Brn
Genetic Background: involves: 129P2/OlaHsd * 129S2/SvPas * 129S4/SvJaeSor * 129S7/SvEvBrd * C57BL/6J * FVB/N

 MP:0010053 decreased grip strength "reduced ability to grasp and hold objects, often measured as time spent hanging from an object or wire" [ISBN:0471316393 "Crawley, JN, What s Wrong with my Mouse: Behavioral Phenotyping of Transgenic and Knockout Mice"]
Show

Allelic Composition: Mdm4tm2Glo/Mdm4tm2.1Glo,Tg(Myh6-cre)2182Mds/0,Trp53tm1Tyj/Trp53tm1Brn
Genetic Background: involves: 129P2/OlaHsd * 129S2/SvPas * 129S4/SvJaeSor * 129S7/SvEvBrd * C57BL/6J * FVB/N

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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